background and objectives: bone marrow necrosis (bmn) is a rare and ominous complication of wide variety of diseases including hematologic malignancy. this study was performed to identify frequency and the underlying associated diseases of marrow necrosis. materials and methods: in this descriptive study, totally 850 bone marrow trephine biopsies related to living patients at the pathology depa...

  Background and Objectives: Bone marrow necrosis (BMN) is a rare and ominous complication of wide variety of diseases including hematologic malignancy. This study was performed to identify frequency and the underlying associated diseases of marrow necrosis. Materials and Methods: In this descriptive study, totally 850 bone marrow trephine biopsies related to living patients at the Pathology ...

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Morphometric methods are commonly used in the diagnosis of diseases of bone. These may be divided into static and dynamic measurements. Static measurements include: (i) the proportion of trabecular surface which is resting, resorbing or covered by osteoid (by a perimeter intersect technique); (ii) the thickness of osteoid seams; and (iii) the proportion of the section occupied by mineralized bo...

Bone diseases are common among middle-aged and elderly people, harm to activities of daily living (ADL) quality life (QOL) for patients. It is crucial search key regulatory factors associated with the development bone explore potential therapeutic targets diseases. Irisin a novel myokine that has been discovered in recent years. Accumulating evidence indicates irisin beneficial effects treatmen...