Given the multi-tissue aspects of osteoarthritis (OA) pathophysiology, translation OA susceptibility genes towards underlying biological mechanism and eventually drug target discovery requires appropriate human in vitro models that incorporate both functional bone cartilage tissue units. Therefore, a microfluidic chip is developed with an integrated fibrous polycaprolactone matrix which neo-bon...

Electrical discharge machining process is one of the most Applicable methods in Non-traditional machining for Machining chip in Conduct electricity Piece that reaching to the Pieces that have good quality and high rate of machining chip is very important. Due to the rapid and widespread use of alloy DIN1.2080 in different industry such as Molding, lathe tools, reamer, broaching, cutting guillot...

Fractures of the third carpal bone (C-3) include small osteochondral fragments (chip fractures), frontal slab fractures of the radial (most common) or intermediate fossae, or both, sagittal slab fractures, most commonly occurring in the radial fossa, and table surface collapse resulting in subchondral lucency of C-3. Small osteochondral fragments are the most common fracture type, and involve o...

Genetic hypercalciuric stone-forming (GHS) rats have increased intestinal Ca absorption, decreased renal tubule Ca reabsorption and low bone mass, all of which are mediated at least in part by elevated tissue levels of the vitamin D receptor (VDR). Both 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) and bone morphogenetic protein 2 (BMP2) are critical for normal maintenance of bone metabolism and bone ...

Materials such as waste tire chips were widely used to improve the strength of soil. The objective of this study is to discuss the residual strength or steady-state behavior of sand-waste tire chip mixtures. A series of undrained monotonic triaxial compression tests were conducted on reconstituted saturated specimens of sand and sand-tire chip mixtures with variation in the tire-chip contents f...

the aim of this study is experimental assay of sensitivity and stability of a bimetallic silver/gold spr sensor chip. this chip utilizes the sensitivity of the silver and the stability of the gold. moreover, the silver layer (instead of usual cr or ti layer) was used as an adhesive intermediate layer between the gold layer and the glass substrate. the optimization of the gold/silver thickness u...

Nowadays, faults and failures are increasing especially in complex systems such as Network-on-Chip (NoC) based Systems-on-a-Chip due to the increasing susceptibility and decreasing feature sizes. On the other hand, fault-tolerant routing algorithms have an evident effect on tolerating permanent faults and improving the reliability of a Network-on-Chip based system. This paper presents reliabili...