In the developing chick hypothalamus, Shh and BMPs are expressed in a spatially overlapping, but temporally consecutive, manner. Here, we demonstrate how the temporal integration of Shh and BMP signalling leads to the late acquisition of Pax7 expression in hypothalamic progenitor cells. Our studies reveal a requirement for a dual action of BMPs: first, the inhibition of GliA function through Gl...

Bone morphogenetic proteins (BMPs) play important roles in embryonic and postnatal development by regulating cell differentiation, proliferation, motility, and survival, thus maintaining homeostasis during organ and tissue development. BMPs can lead to tumorigenesis and regulate cancer progression in different stages. Therefore, we summarized studies on BMP expression, the clinical significance...

Due to the extensive use and improper recycling of traditional plastics, more policies have been issued manage restrict plastics. Therefore, Biodegradable Plastics (BPs), a substitute are widely used in daily life. However, it cannot reach expected degradation effect natural environment, BPs may produce micro-plastics faster than plastics called Microplastics (BMPs). In order explore BMPs, we d...

Mtissbauer measurement, chemical analysis (ratioof Fez+ to total Fe content), analyses ofthe rotational hysteresis loss (Wr) and the magnetic viscosity coefficient (Sv) for bacterial magnetic particles covered with organic thin films (BMPs) were investigated and compared with the results for Fes04 h e particles prepared by a chemical coprecipitation method. The calculated value of the saturatio...

Bone morphogenetic proteins (BMPs) are known as ectopic bone inducers. The FDA approved BMPs (BMP2 and BMP7) for clinical use. However, direct effects of BMPs on endogenous bone metabolism are not yet well known. We recently reported that loss of BMPRIA (ALK3), a potent receptor for BMP2 and BMP4, in osteoblasts unexpectedly increased endogenous bone mass during embryonic and adult stages (ref ...

Bone morphogenetic proteins (BMPs) are a diverse class of molecules with over 20 growth factor proteins that belong to the transforming growth factor-β (TGF-β) family and are highly associated with bone formation and disease development. Aberrant expression of various BMPs has been reported in several cancer tissues. Biological function studies have elicited the dual role of BMPs in both cancer...

Bone morphogenetic proteins (BMPs) are multifunctional cytokines, which are members of the transforming growth factor-beta (TGF-beta) superfamily. Activities of BMPs are extracellularly regulated by BMP-binding proteins, Noggin and Chordin. BMPs bind to two different types of serine-threonine kinase receptors, type I and type II. Two BMP type I receptors and a BMP type II receptor have been ide...

Typically, best management practices (BMPs) are implemented to help sustainable stormwater management in urban areas. Over recent decades the selection of urban stormwater management measures for a site has been a challenge among urban planners where thecriterion based on flood volume no longer suffices for selecting urban drainage solutions. Therefore there is a need to consider a set of holis...

Soil and water are fundamental precious resources for agriculture. In Atlantic Canada (AC), intensive agricultural production systems have led to detrimental environmental effects such as soil erosion the contamination of receiving waters, posing significant threats resilience sustainability agro-ecosystem. Although many beneficial management practices (BMPs) been developed, they all their shor...