نتایج جستجو برای: blood serum metabolites
تعداد نتایج: 975216 فیلتر نتایج به سال:
The absolute quantification of blood plasma metabolites by proton NMR spectroscopy is complicated by the presence of a baseline and broad resonances originating from serum macromolecules and lipoproteins. A method for spectral simplification of proton NMR spectra of blood plasma is presented. Serum macromolecules and metabolites are completely separated by utilizing the large difference in tran...
A liquid-liquid extraction technique and HPLC-DAD method using a C18 column, 5μm (150x4.6mm i.d.) were developed for toxicological drug screening. home-made “N-acetylparoxetine” is used as internal standard. local UV spectra library of over 130 drugs some their metabolites was created. This covers the main therapeutic classes involved in intoxication cases. The procedure successfully applied to...
a research was carried out so as to determine the effect of iranian green tea (igt) powder in diet on blood metabolites and carcass traits of broiler chickens. therefore, considered four treatments consisting (basic diet + igt 5g/kg feed, basic diet + igt 10g/kg feed, basic diet + igt 15g/kg feed and one control diet without additive), and three replicates (15 chicks per repeat). this study las...
Blood is a commonly used biofluid for biomarker discovery. Although blood lipid metabolites are considered to be potential biomarker candidates, their fundamental properties are not well characterized. We aimed to (1) investigate the matrix type (serum vs. plasma) that may be preferable for lipid biomarker exploration, (2) elucidate age- and gender-associated differences in lipid metabolite lev...
Abstract OBJECTIVE To illustrate changes of untargeted metabolomics in patients with glioblastoma IDH wildtype undergoing concurrent radiation therapy (RT) temozolomide (TMZ). This study implemented machine learning (ML) algorithms to predict treatment phase: pre-surgery, post-surgery, pre-radiation, and post based on data. METHODS Thirty-six (18 methylguanine methyltransferase [MGMT] methylate...
BACKGROUND Human plasma and serum are widely used matrices in clinical and biological studies. However, different collecting procedures and the coagulation cascade influence concentrations of both proteins and metabolites in these matrices. The effects on metabolite concentration profiles have not been fully characterized. METHODOLOGY/PRINCIPAL FINDINGS We analyzed the concentrations of 163 m...
Biomarkers will play important roles in disease diagnosis, drug development, and the proper use of drugs. Blood is considered the best biofluid for biomarker research because it is easy to access and a wealth of data are available. However, previous studies revealed that several ionic metabolites showed different levels (including presence or absence) in plasma and serum. Thus, attention should...
an experiment was conducted to study the effects of soybean, linseed and sunflower oil (various sources of fatty acids) with and without l-carnitine supplements (0 and 50 mg kg-1) on performance, blood biochemical parameters and carcass traits of japanese quail. one hundred and ninety-two of 7-day old female japanese quail were randomly assigned to 6 dietary treatments with 4 replicates and fed...
Quantitative NMR-based metabolite profiling is challenged by the deleterious effects of abundant proteins in the intact blood plasma/serum, which underscores the need for alternative approaches. Protein removal by ultrafiltration using low molecular weight cutoff filters thus represents an important step. However, protein precipitation, an alternative and simple approach for protein removal, la...
this study was conducted to investigate the effects of l-carnitine and different levels of animal fat on performance, carcass characteristics and some blood parameters of broiler chickens. two hundred one-day old male broiler chicks were allotted to5 treatments in 4 replicates and 10 birds in each replicate. dietary treatments consisted of: 1) diet with 5% vegetable oil (t1), 2) diet with 5% ve...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید