The human population genetics incorporates study of biology and environmental factors, as well as the forces of micro-evolution leading to macro-evolution, which ultimately influences the structure of humanpopulations. In the present paper and attempt has been made to a give a brief review of the genetics and distribution of some of the polymorphic traits blood groups, human leucocyte antig...

background: animal suitable models are very useful tools in the studies of complicated diseases. in this way we can study the heterogeneity of human genome and also we can minimize the effect of environmental factors in the incidence of cancers. in this study the expression of vwf and pcna in tumors was determined by immunohistochemistry and also we measured three cancer markers and two blood f...

this article reviews the recently published data on the diagnosis of cancer with proteomics, including the major proteomics technologies and promising strategies for biomarker discovery and development.  most of the tumor markers are proteins that either numerically increase in response to the alteration of cancer conditions or are produced by cancer cells. however, they are natural compounds o...

the above investigation represents one of ihe few studies carried out in the field of population genetics in iran. the differences in all three groups of siudies which have been carried oui by blood transfusion centres of the imperial army, red lion and sun and teheran university, inspired us to carry out further investigations on abo blood grouping and rh typing in order to obtain the result o...

background: safety of blood products and plasma derivates is one of main concerns in transfusion sector. screening of donated blood became an emerging item to large extent because of hepatitis c and b virus, (hcv, hbv) and hiv epidemics especially in blood donation campaign following disasters. in this study we aim to evaluate the pattern of variation of viral infection markers donated at three...

Alzheimer Disease (AD) is a neurodegenerative disorder and the most common form of dementia. Increasing evidence suggests that Alzheimer's disease pathogenesis is not restricted to the neuronal compartment, but includes strong interactions with immunological mechanisms in the brain. In vitro and animal studies have linked neuroinflammation to Alzheimer's disease (AD) pathology. Studies on marke...

Background and Aims: Total hip arthroplasty (THA) is a common orthopedic surgery. The main focus in the research of THA is immune responses in these patients following the blood transfusion.Therefore, in this study, we evaluated the immune modulation indexes such as T cell amplification, Tcell surface markers and also production of cytokines in the patients undergoing THA surgery following bloo...