Background: The mechanisms underlying cerebral hypercapnic vasodilatation are not fully understood. Objective: To investigate the role of nitric oxide (NO) and ATP-sensitive potassium (KATP) channels in basal blood flow regulation and hypercapnia-induced vasodilatation in rabbit cerebral blood vessels. Methods: The change in cerebral blood flow was measured by a laser Doppler flowmeter in 18 Ne...

introduction:adenosine as a potent vasodilator has physiological role in regulation of regional cerebral blood flow (rcbf). metod: laser-dِoppler flowmetry technique was used to study pial vessels blood flow responses to adenosine receptors agonists and antagonist. male sprague dawley rats (250-350g) that were housed in standard conditions, were anesthetized with urethane (1.5g/kg). adenosine (g...

purpose: to assess orbital color doppler ultrasonography (cdu) parameters of patients with manifest hyperopia in comparison to the emmetropes methods: forty eyes of 40 patients presenting with manifest hyperopia were included into the study. forty eyes of 40 emmetropes healthy volunteers also were examined as the control group. we have evaluated ophthalmic artery (oa), central retinal artery (c...

ndometrial vasculature has been shown to play an important role in the early endometrial response to the implanting blastocyst, and vascular changes may contribute to uterine receptivity . the aim of this study was to investigate the role of endometrial and subendometrial vascularity and thickness in uterine receptivity in infertile women treated with assisted reproductive technologies (art). a...

the cytotoxic activity of natural killer cells is usually tested by radioactive assay csi cr release assay), which detects the release of cytoplasmic contents after plasma membrane disintegration of dying cells. in contrast to this indirect evaluation of cytotoxicity, the assessment of cell damage by flow cytometry aims to provide a more exact characterization of the death pathway via detection...

background: to determine whether islamic fasting would change cerebral blood flow during ramadan. methods: the study group comprised 20 subjects (16 males and 4 females) on a regimen of 1 month food and water intake restriction, according to islamic fasting ritual. subjects were evaluated for cerebral bolo flow through a middle cerebral artery (mca) by means of transcranial doppler (tcd), the d...

introduction: endothelium and smooth muscle dysfunction are the most important complications of diabetes. in type 1 diabetic patients, absence of insulin leads to vasoconstriction and lower skin blood perfusion. release of some mediators by endothelium which is induced by insulin causes vasodilation, but the exact mechanism of insulin vasodilatory effect is not detected properly. at present stu...

Objective(s): One applications of nanotechnology is in the area of medicine which is called nanomedicine. Primary instruments in nanomedicine can help us to detect diseases and used for drug delivery to inaccessible areas of human tissues. An important issue in simulating the motion of nanoparticles is modeling blood flow as a Newtonian or non-Newtonian fluid. Sometimes blood flow is simulated ...

In this investigation, a mathematical model for studying oscillatory flow of blood in a stenosed artery under the influence of transverse magnetic field through porous medium has been developed. The equations of motion of blood flow are solved analytically. The analytical expressions for axial velocity, volumetric flow rate, pressure gradient, resistance to blood flow and shear stress have been...