Colorectal endoscopic submucosal dissection (ESD) has become the standard of care for large superficial colorectal neoplasms, and allows en bloc resection of very large lesions [1]. The first goal of this technique is en bloc and R0 resection of large colorectal lesions to allow good pathological examination and determination of whether the endoscopic resection was curative. Such a conclusion i...

BACKGROUND Endoscopic submucosal dissection (ESD) is a novel endoluminal technique that permits the resection of gastric neoplasms. AIM To analyse the feasibility of snaring as the final step of ESD. PATIENTS AND METHODS One hundred and ninety-nine consecutive gastric neoplasms resected by four ESD experts from January 2004 to May 2007 were investigated. Forty-five (22.6%) were finally rese...

BACKGROUND Distinction of parathyroid cancer from atypical parathyroid adenoma (APA) at operation is difficult. The aim of this study was to determine whether parathyroid cancer and APA have different operative findings and long-term outcomes. METHODS A retrospective review was undertaken of patients with suspicious or malignant parathyroid tumours treated between 1974 and 2005. Parathyroid c...

BACKGROUND In most of the reported series, almost half of the giant-cell tumors involved the knee region. The characteristics of the lesions were usually benign but often locally aggressive and easily recurrent neoplasms. Some surgeons performed intralesional excision combined with local adjunctive chemical coagulant, and bone grafting or methylmethacrylate cement packing. These methods could b...

BACKGROUND AND IMPORTANCE Primary tumors of the spine are considered for en bloc resection to improve local control and even obtain cure. Anatomic restrictions often prohibit extensive resections with negative margins that are safe and feasible. We report the first case involving a patient with a large chordoma of the thoracic spine who underwent a successful 5-level spondylectomy with bilatera...

AIM Today, free margin surgery is the gold-standard management for soft-tissue sarcoma patients and one of the most important predictors of recurrence and survival. To obtain optimal results, a multidisciplinary approach is necessary. The aim of this study was to evaluate the evolution of patients with RPS treated by «en bloc«surgical resection versus those treated with enucleation in the first...

BACKGROUND Circumferential mucosal incision around a lesion is effective for reliable endoscopic mucosal resection. However, mucosal incision with a needle knife is difficult, even with submucosal injection of normal saline solution. To make needle-knife incision easier and safer, sodium hyaluronate has been used rather than normal saline solution. The aim of this study was to evaluate the clin...

OBJECTIVE The aim of this paper was to describe the operative details for en bloc removal of the adnexal tumor, uterus, pelvic peritoneum, and rectosigmoid colon with colorectal anastomosis in advanced epithelial ovarian cancer patients with widespread pelvic involvement. METHODS The patient presented with good performance status and huge pelvic tumor extensively infiltrating into adjacent pe...

Endoscopic submucosal dissection (ESD) is now an approved technique for removal of superficial tumors in the upper and lower gastrointestinal tract. The European Society of Gastrointestinal Endoscopy (ESGE) recommends ESD as the first treatment for superficial SCC and for early gastric cancer [1]. In Barrett’s cancer, however, ESD’s role and indications are still debated by “pro” and “con” expe...

BACKGROUND AND STUDY AIMS Endoscopic submucosal dissection (ESD) has been developed to overcome the limitations of endoscopic mucosal resection (EMR). We aimed to compare the outcomes of these two methods. METHODS Databases, including Pubmed, EMBASE, and The Cochrane Library, were searched to identify studies comparing ESD with EMR for premalignant and malignant lesions of the gastrointestina...