sickle cell disease is a genetic haemoglobinopathy with consequent haemolysis and anaemia. it is of interest to study its effect on red cell indices beside haemoglobin concentration.the objective of the study is to determine the values of red cell indices in preschool-age children with sickle cell anaemia.we conducted a cross-sectional study including 97 children with sickle cell anaemia aged s...

A 37-year-old man with no significant past family or personal medical history was admitted to the hospital for persistent eosinophilia detected during a routine check-up. He denied recent travel and was not a smoker, alcoholic, or drug addict. He did not have any history of allergic disease and was not exposed to any toxins or pesticides. Physical examination was normal. His complete blood exam...

OBJECTIVE To analyze the expression of various antigens on the leukemic blasts and to determine the hematological parameters, in Acute Lymphoblastic Leukemia (ALL) patients at presentation. STUDY DESIGN Observational study. PLACE AND DURATION OF STUDY King Edward Medical University, Lahore and Hameed Latif Hospital, Lahore, from February 2013 to March 2014. METHODOLOGY A total of 50 newly...

background: automatic cell counter devises make the cbc differential very easy and delivering the results in few second. however, the problem with this device is facing a flag requires a time-consuming microscopic review of the specimen which causes unacceptable wait times for patient as well as costs for laboratories. in this study, we calculated the validity of wbc diff flags in sysmex xt-180...

Pulmonary leukostasis is a rare but serious and often fatal complication of chronic myeloid leukemia (CML) in blast crisis and acute myeloid leukemia. Treatment options are limited for these patients. Imatinib mesylate (STI-571, Gleevec, Novartis) is a potent and selective inhibitor of the BCR-abl tyrosine kinase, the molecular abnormality that causes CML. The case of a 74-year-old man with a h...

BACKGROUND Treatment response has become one of the most important prognostic factors in childhood acute lymphoblastic leukemia. We evaluated the significance of the complete clearance of peripheral leukemic blasts on survival in children with acute lymphoblastic leukemia. DESIGN AND METHODS Seven hundred and fifty-four children diagnosed with acute lymphoblastic leukemia, consecutively enrol...

Reliable automated blood cell characterization and quantification remain challenging in pathologic samples, whereas slide reviews due to unnecessary flagging should be avoided. We compared 4 modern hematology analyzers-Abbott Sapphire, Siemens Advia 120, Sysmex XE-2100, and Beckman Coulter DxH 800-regarding complete blood cell count (CBC), leukocyte differential count, and flagging efficacy in ...

background & objective: there are many common infections and inflammations among people over the world. this demands an affordable and reliable test with high sensitivity/specificity to predict or confirm the diagnosis of such cases in routinely clinical practice. in the present study, we aimed to find any potential correlation between serum levels of ggt and crp- q and/or hs- crp and wbc c...

the objective of the present study was to estimate genetic trends for lactation milk yield, persistency of milk yield, somatic cell count and interval between first and second calving in holstein dairy cows of iran. the dataset consisted of 210,625 test day and 25,883 first parity cows with milk yield recorded from july 2002 to september 2007 comprising 97 herds in iran. breeding values of anim...