نتایج جستجو برای: bk

تعداد نتایج: 6583  

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2001
Y Takei T Tsuchida Z Li J M Conlon

A peptide with bradykinin (BK)-like immunoreactivity was isolated from an incubate of heat-denatured eel plasma with porcine pancreatic kallikrein. The purified peptide had the following amino acid sequence: Arg-Arg-Pro-Pro-Gly-Ser-Trp-Pro-Leu-Arg. This decapeptide, named eel [Arg(0)]BK, was identical to two previously identified BK homologs from cod and trout. High conservation of the BK seque...

Journal: :Pharmacological research 2011
Lajos Gera Caroline Roy Marie-Thérèse Bawolak Johanne Bouthillier Albert Adam François Marceau

Bradykinin (BK) is a vasoactive nonapeptide cleaved from circulating kininogens and that is degraded by angiotensin converting enzyme (ACE). It has been reported that the PR3 protease from human neutrophil releases an alternate peptide of 13 amino acids, Met-Lys-BK-Ser-Ser, from high molecular weight kininogen. We have studied vascular actions of this kinin. Its affinity for recombinant B₁ and ...

2014
Hui Xu Hannah Garver Roxanne Fernandes James J. Galligan Gregory D. Fink

Xu H, Garver H, Fernandes R, Galligan JJ, Fink GD. Altered L-type Ca channel activity contributes to exacerbated hypoperfusion and mortality in smooth muscle cell BK channel-deficient septic mice. Am J Physiol Regul Integr Comp Physiol 307: R138–R148, 2014. First published May 14, 2014; doi:10.1152/ajpregu.00117.2014.—We determined the contribution of vascular large conductance Ca -activated K ...

Journal: :Diyala Journal of Medicine 2022

Background: BK virus, a human polyomavirus, causes nephropathy and allograft loss in renal transplant recipients. Although it was discovered 1971, understanding of the humoral immune response to BKV is limited.
 Objective: To serological detection level estimation anti-BK-IgG renal-transplanted recipients healthy blood donors as control.
 Patients Methods: Serum samples were collected...

2014
Alex M. Dopico Anna N. Bukiya Gilles E. Martin

In most tissues, the function of Ca(2+)- and voltage-gated K(+) (BK) channels is modified in response to ethanol concentrations reached in human blood during alcohol intoxication. In general, modification of BK current from ethanol-naïve preparations in response to brief ethanol exposure results from changes in channel open probability without modification of unitary conductance or change in BK...

ژورنال: ارمغان دانش 2015
روزبه, جمشید, امامی, امیر , باصری صالحی, مجید , معطری, آفاق , یعقوبی, رامین ,

زمینه و هدف: پولیوماویروس BK‌ یک عفونت فراگیر باشیوع بیش از 80%در دنیا میباشد. یکی از دلائل اهمیت پولیوماویروس BK ، بروز آسیبهای کلیوی و رد پیوند در بیماران گیرنده پیوند کلیه می باشد. ناحیه غیرکدشونده کنترلی ژنوم پولیوماویروس نقش تنظیمی در بیان ژنها و تکثیر این ویروس دارد، این مطالعه با هدف راه اندازی روشی مولکولی حساس و دقیق بمنظور بررسی الگوی ژنتیکی این ناحیه در بیماران انجام گرفت. روش بررسی:...

Alireza Najafpour, Hadi Dadafarid

Objective- To evaluate the effects of bupivacaine (B), ketamine (K), and a combination of bupivacaine and ketamine (BK) after lumbosacral epidural analgesia in sheep.   Design- Experimental study.   Animals- Nine healthy male and non-pregnant female Iranian Chall sheep with mean body weight of 38.9 ± 15.1 kg.   Procedures- Animals were selected randomly and three treatments administered. The ...

Journal: :jundishapur journal of microbiology 0
gholam abbas kaydani health research institute, infectious and tropical diseases research center, faculty of paramedical, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; health research institute, infectious and tropical diseases research center, faculty of paramedical, ahvaz jundishapur university of medical sciences, ahvaz, ir iran. tel: +98-9163018564 manoochehr makvandi virology department, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, ir iran alireza samarbafzadeh virology department, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, ir iran heshmatollah shahbazian golestan hospital, ahvaz jundishapur university of medical sciences, ahvaz, ir iran mojtaba hamidi fard virology department, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, ir iran

background bk virus (bkv) belongs to the human polyomaviridae and the primary bkv infection is occurred during childhood then the virus could be latent through life, especially in the kidneys and urinary system. it became reactive after an immunocompromised status, such as pregnancy or transplantation. isolated bkv from different locations of the world is grouped into four subtypes using serolo...

2018
Hélène Bachelard Xavier Charest-Morin François Marceau

We previously reported hypotensive and vasodilator effects from C-terminally extended bradykinin (BK) sequences that behave as B2 receptor (B2R) agonists activated by vascular or plasma peptidases. D-Arg0-BK-Arg-Arg (r-BK-RR) is a novel prodrug peptide hypothetically activated by two catalytic cycles of Arg-carboxypeptidases (CPs) to release the direct agonist D-Arg0-BK. N-terminally extending ...

2000
ANTTI KUOPPALA KEN A. LINDSTEDT JUHANI SAARINEN PETRI T. KOVANEN JORMA O. KOKKONEN Ken A. Lindstedt Juhani Saarinen Petri T. Kovanen

Kuoppala, Antti, Ken A. Lindstedt, Juhani Saarinen, Petri T. Kovanen, and Jorma O. Kokkonen. Inactivation of bradykinin by angiotensin-converting enzyme and by carboxypeptidase N in human plasma. Am J Physiol Heart Circ Physiol 278: H1069–H1074, 2000.—Because bradykinin (BK) appears to have cardioprotective effects ranging from improved hemodynamics to antiproliferative effects, inhibition of B...

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