Bitter melon (Momordica charantia L.) is a tropical fruit claimed to have medicinal properties associated with its content of phenolic compounds (TPC). The aim of the study was to compare water with several organic solvents (acetone, butanol, methanol and 80% ethanol) for its efficiency at extracting the TPC from freeze-dried bitter melon powder. The TPC of the extracts was measured using the F...

Our aim was to optimise the encapsulation of an aqueous bitter melon extract by spray-drying with maltodextrin (MD) and gum Arabic (GA). The response surface methodology models accurately predicted the process yield and retentions of bioactive concentrations and activity (R² > 0.87). The optimal formulation was predicted and validated as 35% (w/w) stock solution (MD:GA, 1:1) and a ratio of 1.5:...

Diabetes, obesity, and metabolic syndrome are becoming epidemic both in developed and developing countries in recent years. Complementary and alternative medicines have been used since ancient era for the treatment of diabetes and cardiovascular diseases. Bitter melon is widely used as vegetables in daily food in Bangladesh and several other countries in Asia. The fruits extract of bitter melon...

Present study aimed to determine the effect of 'bitter melon', a popularly used fruit in Bangladesh and several other Asian countries, on high-fat-diet-induced type 2 diabetes. To investigate the effect, ethanol extract from bitter melon (BME) as a dietary supplement with mouse chow was used. BME was found to significantly attenuate the high-fat diet (HFD) -induced body weight and total fat mas...

the majority of the antioxidant and antidiabetic activities of fruits are anthocyanins, a group of polyphenolics that are responsible for the color of many fruits, vegetables and flowers. the harvesting time, storage conditions, maturity, extraction steps etc. are very important for the biological activities based on the alteration of chemical composition. the free radical scavenging and antidi...

Purpose: To evaluate the contents of carotenoids, triterpenoids, and phenylpropanoids in different parts white bitter melon.Methods: We evaluated accumulation 2 10 11 melon, including fruits at four developmental stages using HPLC.Results: Charantin, lutein, rutin were main phenylpropanoids, respectively. The triterpenoids (momordicine charantin), carotenoids (antheraxanthin, violaxanthin, α-ca...

The purpose of this study was to investigate the nutrient and phytochemical composition of bitter melon leaves under varying maturity levels and drying techniques. Fresh, oven-dried, and freeze-dried leaves were evaluated over 3 maturity stages. In fresh leaves at various stages, crude fat, crude protein, and soluble dietary fiber contents ranged from 4.2% to 13.6%, 6.4% to 23.1%, and 0.04% to ...

BACKGROUND Bitter Melon (BM) is known for its hypoglycemic effect and is commonly used in populations. OBJECTIVES This study examined the effects and safety of bitter melon fruit in laboratory mice. MATERIALS AND METHODS In this experimental study 70 male mice (25-30 gr) were randomly divided into 7 groups. The mice were injected intraperitoneally with single doses of 0, 100, 500, 1000, 200...

Fopius arisanus and Psyttalia fletcheri are egg and larval parasitoids, respectively, of tephritid fruit flies including the melon fly, Bactrocera cucurbitae. We investigated the consequences of parasitization when eggs or larvae of melon flies were exposed to F. arisanus or P. fletcheri alone, or to both in succession. In addition, we evaluated the effect of fruit substrates on host preference...