how to cite this article: khalessi n, khosravi n, mirjafari m, afsharkhas l. plasma ammonia levels in newborns with asphyxia. iran j child neurol. winter 2016; 10(1):42-46. abstract objective perinatal asphyxia may result in hypoxic damage in various body organs, especially in the central nervous system. it could induce cascade of biochemical events leading to the cell death and metabolic chang...

BACKGROUND The current decline in under-five mortality shows an increase in share of neonatal deaths. In order to address neonatal mortality and possibly identify areas of prevention and intervention, we studied causes of admission and cause-specific neonatal mortality in a neonatal care unit at Kilimanjaro Christian Medical Centre (KCMC) in Tanzania. METHODS A total of 5033 inborn neonates a...

The aim of this study was to establish the outcome of very severe birth asphyxia in a group of babies intensively resuscitated at birth. 48 infants, born between 1966 and 1971 inclusive, were selected; 15 were apparently stillborn and 33 had not established spontaneous respirations by 20 minutes after birth. One-half of them died, but 3 to 7 years later three-quarters of the survivors are appar...

As infant mortality rates decline steadily in South Asia, largely through a fall in post-neonatal mortality, increasing attention is turning to the perinatal period(l). Many studies in this region have demonstrated birth asphyxia to be a major cause of perinatal death(2). However, the contribution of birth asphyxia to the burden of neurodisability in developing country populations is still to b...

OBJECTIVES To compare the Conventional, Specified, Expanded and Combined Apgar scoring systems in predicting birth asphyxia and the adverse early neurologic outcomes. METHODS This prospective cohort study was conducted on 464 admitted neonates. In the delivery room, after delivery the umbilical cord was double clamped and a blood samples was obtained from the umbilical artery for blood gas an...

OBJECTIVE Hypoxic ischemic encephalopathy (HIE) is a major cause of permanent neurological disabilities. Perinatal asphyxia may induce neonatal mortality after birth or neurological impairment among survivors. There are no reliable methods for identifying infants at risk for this disorder. METHODS We measured the ratio of lactate/creatinine (L/C) in urine by proton nuclear magnetic resonance ...