نتایج جستجو برای: biopharmaceutics
تعداد نتایج: 271 فیلتر نتایج به سال:
Microbiology and Cell Science Department (R.Z., C.L.-O., V.d.C.-L.) and Horticultural Sciences Department (O.F., K.W.E., A.D.H.), University of Florida, Gainesville, Florida 32611; Laboratory of Biochemistry and Molecular Biology, Department of Biosciences, Biotechnologies, and Biopharmaceutics, University of Bari, 70125 Bari, Italy (G.A., A.C., A.R., F.P.); and Department of Molecular and Cell...
The Biopharmaceutics Classification System (BCS) is the result of continuous efforts in mathematical analysis for the elucidation of the kinetics and dynamics of the drug process in the gastrointestinal tract (GIT) for NDA (New Drug Application) and ANDA (Abbreviated New Drug Application) filings and biowaivers. This step reduces timelines in the new drug development process, both directly and ...
Department of Pharmaceutics and Biopharmaceutics, Showa Pharmaceutical University (A.M., M.K., H.S., A.T., M.H., M.F., Y.W.), Machida, Tokyo 194-8543, Japan. Project III, National Institute of Biomedical Innovation (H.M.), Osaka 567-0085, Japan. Department of Bacterial Toxinology, Research Institute for Microbial Diseases, Osaka University (Y.H.), Osaka 565-0871, Japan. JPET Fast Forward. Publi...
Abbreviations: UHPLC: Ultra-High-Performance Liquid Chromatography; HESI: Heated Electrospray Ionization; MS: Mass Spectrometry; MS/ MS: Tandem Mass Spectrometry; BCS: Biopharmaceutics Classification System; FDA: Food and Drug Administration; PK: Pharmacokinetic; IS: Internal Standard; m/z: mass-to-charge ratio; Cmax: Peak Plasma Concentration of Drug; Tmax: Time required to reach the peak plas...
Drug dissolution, release and uptake are the principal components of oral drug absorption. All these processes take place in the complex milieu of the gastrointestinal tract and they are influenced by physiological (e.g. intestinal pH, transit time) and physicochemical factors (e.g. dose, particle size, solubility, permeability). Due to the enormous complexity issues involved, the models develo...
Molecular Materials Centre, School of Chemical Engineering and Analytical Science, The University of Manchester, PO Box 88, Sackville Street, Manchester M60 1QD, England, Process Engineering Group, PR&D, AstraZeneca, Silk Road Business Park, Charter Way, Macclesfield, Cheshire SK10 2NA, England, and Preformulation and Biopharmaceutics, PAR&D, AstraZeneca, Silk Road Business Park, Charter Way, M...
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