Strategically, ‘biomaterials research’ should be refocusing its science on new areas – but it has not! Traditionally, biomaterials research has been heavily leveraged in ‘synthetic biomaterials product-testing’, but it should be moving towards ‘biological materials and clinical research’. There is an adage (Lubin’s Rule) that says ‘If another scientist thought your research was more important t...

The past half century has seen explosive growth in the use of medical implants. Orthopedic, cardiac, oral, maxillofacial and plastic surgeons are examples of medical specialists treating millions of patients each year by implanting devices varying from pace makers, artificial hip joints, breast and dental implants, to implantable hearing aids. All such medical implants make use of special mater...

Impaired wound healing is the leading cause of non-traumatic lower limb amputation in people with diabetes mellitus. Skin substitutes engineered from biomaterials currently play an important role in the healing process of diabetic wounds, especially those wounds that fail to show progress after standard wound care. This article summarizes current developments of biomaterials used for promoting ...

Over the last 4 decades innovations in biomaterials and medical technology have had a sustainable impact on the development of biopolymers, titanium/stainless steel and ceramics utilized in medical devices and implants. This progress was primarily driven by issues of biocompatibility and demands for enhanced mechanical performance of permanent and non-permanent implants as well as medical devic...

Biomaterials are widely used to help treat neurological disorders and/or improve functional recovery in the central nervous system (CNS). This article reviews the application of biomaterials in (i) shunting systems for hydrocephalus, (ii) cortical neural prosthetics, (iii) drug delivery in the CNS, (iv) hydrogel scaffolds for CNS repair, and (v) neural stem cell encapsulation for neurotrauma. T...

Biomaterial is a nonviable substance used in a medical device intended to interact with biological systems. Their usage within a physiologic medium needs the characteristic features such as efficient and reliable. These characteristic features have provided with a suitable combination of chemical, mechanical, physical and biological properties [2]. Nowadays, biomaterials are commonly used in va...

OBJECTIVES To determine the adjunctive effect of grafting biomaterials/biological agents with open flap debridement (OFD) in the treatment of deep intraosseous defects. BACKGROUND No systematic review of treatment outcomes in patients who received graft biomaterials or biological agents have been published. METHODS A rigorous systematic review of randomized controlled trials of at least 6-m...