BACKGROUND Biomarkers may help clinicians predict cardiovascular risk. We aimed to determine if the addition of endocrine, metabolic, and obesity-associated biomarkers to conventional risk factors improves the prediction of cardiovascular and all-cause mortality. METHODOLOGY/PRINCIPAL FINDINGS In a population-based cohort study (the Study of Health in Pomerania) of 3,967 subjects (age 20-80 y...

Obesity is a major risk factor for cardiovascular diseases, but the mechanisms for increased cardiovascular risk in obesity are still unclear. Inflammation and increased oxidative stress are two potential mechanisms proposed to play a major role in the morbidity associated with obesity. Studies that investigate these mechanisms rely on biomarkers, but validated biomarkers for obesity-related ca...

Cardiovascular disease (CVD), especially heart failure (HF) as its common final pathway, is the leading cause of morbidity and mortality worldwide. Furthermore, oxidative and inflammatory processes represent fundamental underlying mechanisms for the development and progression of HF. Of interest, in recent years the development of markers with diagnostic and prognostic value for this pathology ...

breast cancer is the most important and prevalent cancer in women that can be managed if detected in the early stages. recently, there has been much focus on the use of epigenetic changes such as dna methylation in early detection of cancer. as recent research has put forth dok7 cpg island methylation as an epimarker, in the present study, using a quantification method, a cohort of iranian spor...

to date, most studies have focused on continuous aerobic training and there is not comprehensive information about the influence of discontinuous aerobic training on cardiovascular risk biomarkers. taking this into consideration, the purpose of the present study is to investigate the influence of an 8-week discontinuous aerobic training program (3×10 min) on cardiovascular risk biomarkers in in...

background: given the high prevalence of type ii diabetes and its complications, the evidence regarding the beneficial effects of probiotic yogurt on some cardiovascular biomarkers in diabetic patients is worthy of investigation. aim: to investigate the effect of probiotic yogurt on blood glucose level and cardiovascular biomarkers in patients with type ii diabetes. method:this randomized, clin...