Long-term studies in the field of radiation cytogenetics have resulted in the discovery of relationship between induction of chromosome aberrations and the type of ionizing radiation, their intensity and dose. This has served as a basis of biological dosimetry as an area of application of the revealed relationship, and has been used in the practice to estimate absorbed doses in people exposed t...

Since 1997 almost 400 patients with mainly head and neck cancer have been treated successfully with the rasterscan technique [1] at GSI. Due to interplay between scanned beam and organ motion, it is not possible to treat tumor sites influenced by respiratory motion. A potential technique to overcome this problem is tracking [2], where the beam position is adapted to a moving target in 3D based ...

Development of radiation technology has resulted in increasing numbers of people working with it. Therefore it has increasingly been important to monitor the radiation in order to ensure public safety. Physical dosimetry plays an important role in monitoring. But a need arise for biological dosimetry where physical dosimetry is absent or its presence is insufficient. In this study Co-60 gamma r...

PURPOSE To check the bioeffects of the components of magnetic resonance imaging (MRI). MRI is based on an assumed harmless interaction between certain nuclei in the body when placed in a strong magnetic field and radio wave fields. There are three key factors actuating on the examining body: a powerful static magnetic field (SMF), magnetic gradient fields (MGFs), and pulsed radiofrequency (RF) ...

Abbreviations: CPD: Cyclobutane Pyrimidine Diner; DLR: German Aerospace Center; ds-break: Double Strand Break; EST: Experiment Sequence Test; EVT: Experiment Verification Test; ISS: International Space Station; IWF: Institut für Weltraumforschung; LEO: Low Earth’s Orbit; OD: Optical density [log(I0/I)]; PCR: Polymerase Chain Reaction; PLC: Payload Computer; RGB: Research Group for Biophysics; s...

In terms of biological dosimetry at the time of radiation exposure, the dicentric chromosome (Dic) assay (DCA) is the gold standard for assessing for the acute phase and chromosome translocation (Tr) analysis is the gold standard for assessing the chronic phase. It is desirable to have individual dose-response curves (DRCs) for each laboratory because the analysis criteria differ between labora...

BACKGROUND AND OBJECTIVE Professional radiation workers are occupationally exposed to long-term low levels of ionizing radiation. Occupational health hazards from radiation exposure, in a large occupational segment of the population, are of special concern. Biological dosimetry can be performed in addition to physical dosimetry with the aim of individual dose assessment and biological effects. ...