Biodegradable polymers have attracted a lot of attention in the recent years. These biopolymers are large macromolecules composed of single, repeating monomer units. They are of very high molecular weight and their material characteristics vary according to the nature of their monomer composition. Over the last decade, depletion in the petroleum reserves has resulted in the emergence of biodegr...

In the last years biologically stable biomaterials gives their place to biodegradable biomaterials in packaging, agriculture, medicine, and other application areas. For applications in medicine this happens because of the some problems caused by the regeneration ability of the living tissues and toxic effect of stable polymers. By products of biodegradable polymers leaves no residual mass at th...

This paper completes the model of biodegradation for biodegradable polymers that was previously developed by Wang et al. (Wang Y, Pan J, Han X, Sinka, Ding L. A phenomenological model for the degradation of biodegradable polymers. Biomaterials 2008;29:3393-401). Crystallisation during biodegradation was not considered in the previous work which is the topic of the current paper. For many common...

While surface modification is well suited for imparting biomaterials with specific functionality for favorable cell interactions, the modification of degradable polymers would be expected to provide only temporary benefit. Bulk modification by incorporating pendant reactive groups for subsequent functionalization of biodegradable polymers would provide a more enduring approach. Towards this end...

BACKGROUND With the thrombogenic tendency and permanent implant nature of metallic stents, synthetic polymers have been proposed as candidate materials for stents and local drug delivery designs. We investigated the biocompatibility of several synthetic polymers after experimental placement in the coronary artery. METHODS AND RESULTS Five different biodegradable polymers (polyglycolic acid/po...

During the past two decades significant advances have been made in the development of biodegradable polymeric materials for biomedical applications. Degradable polymeric biomaterials are preferred candidates for developing therapeutic devices such as temporary prostheses, three-dimensional porous structures as scaffolds for tissue engineering and as controlled/sustained release drug delivery ve...

Use of biodegradable polymers for biomedical applications has increased in recent decades due to their biocompatibility, biodegradability, flexibility, and minimal side effects. Applications of these materials include creation of skin, blood vessels, cartilage scaffolds, and nanosystems for drug delivery. These biodegradable polymeric nanoparticles enhance properties such as bioavailability and...

Synthetic polymers have been widely used in making various medical devices, such as disposable supplies, implants, drug delivery systems and tissue engineering scaffolds. The advantages of using polymers, as biomaterials, are their manufacturability. Polymers are easy to fabricate into various sizes and shapes compared to metals and ceramics. They are also light in weight and with a wide range ...

Within the past decade, researchers in the field of tissue engineering have recognized the need for newmaterials with soft and elastic properties. As a result, many groups have focused on the synthesis, characterization, and application of materials with a wide range of biodegradable and elastomeric properties.1 The combination of these polymers with Micro–Electro–Mechanical Systems (MEMS) tech...

Objectives Production of effective tuberculosis (TB) vaccine is necessity. However, the development of new subunit vaccines is faced with concerns about their weak immunogenicity. To overcome such problems, polymers-based vaccine delivery systems have been proposed to be used via various routes. The purpose of this study was to determine the potential of polymeric particles as future vaccine de...