urine level distribution of antitumor agents, due most likely to the lack of highly sensitive bioassay methods for measuring the concentrations of biologically active ma terials at the low doses generally tolerated by the host. In the present study, cell culture bioassay procedures were used to determine the levels of several clinically use ful or experimental agents in blood and urine after admin

A novel, partial life-cycle bioassay using Chironomus tentans in artificial streams was developed for evaluating the effects of metal mine effluent. The utility of this bioassay was compared to an existing beaker life-cycle bioassay under laboratory conditions. Chironomus tentans larvae were exposed to 45% (v/v) treated metal mine effluent from day 11 through hatching of the second generation. ...

A bioassay that used postexposure feeding depression in Daphnia magna Straus as an endpoint previously had been developed under laboratory conditions. Laboratory studies revealed that this was a sensitive, robust endpoint, which could potentially be used in an in situ bioassay. This study adapted the laboratory bioassay for use in the field and deployed D. magna in situ at four known or suspect...

A statistical study of fitting log-normal distributions to air sampling concentrations and random intakes is reported in this paper. An improved method on the approximation of a sum of log-normal distributions to a log-normal distribution is used to forecast bioassay results and their uncertainties. These methods can be used in the design and implementation of air control monitoring and bioassa...

Endophytic microorganism live inter or intra cellularly in most of the plant tissues without causing any disease symptoms. Endophytes are known to produce plant growth promoting compounds. Cytokinin is a group of plant growth regulators (PGRs) and can be exploited in agriculture for both pre-harvest and postharvest management of leafy vegetables, fruits and cut flowers. The objective of this st...

Aedes aegypti L. is the mosquito vector of yellow fever, dengue, zika, and chikungunya viruses. The prevention control such diseases usually rely on use chemicals, that can cause harm to human health environment. Vegetable oils with larvicidal activity are used as an alternative tool this insect. This study aimed evaluate vegetable from Caryocar coriaceum, Mauritia fIexuosa, Carapa guianensis, ...

Tumor detection can be carried out via the detection of proteins, such as p53, which is known to play vital role in more than 50% of all cancers affecting humans. Early diagnosis of tumor detection can be achieved by decreasing the lower detection limit of p53 bioassays. Microwave-accelerated bioassay (MAB) technique, which is based on the use of circular bioassay platforms in combination with ...