Lycopene is the most abundant carotenoid found in tomatoes and thus has been touted as the bioactive component for the reduced risk of chronic diseases such as prostate cancer. We and others hypothesize that lycopene metabolites are responsible for positively modulating biomarkers and risk factors for the prevention of chronic diseases. Lycopene metabolites circulate in serum and accumulate in ...

Medicinal plants containing essential bioactive ingredients are used to cure disease or disorder since time immortal. One of the aims of medicinal plant research is the isolation and identification of markers/ bioactive compounds. Isolation of the markers compounds and bioactive plant constituents has always been a challenging task for the researchers. Separation of these components from the me...

Elektrokinetické vlastnosti zmesí minerálov Elektroforetický rozptyl svetla (ELS) je nová experimentálna technika umožňujúca merať spectrum elektroforetickej pohyblivosti alebo zeta (ξ) potenciálu skupiny častíc. Toto spectrum odráža distribúciu náboja a čiastočne distribúciu rozmeru týchto častíc. Avšak, okrem modálnej hodnoty napr. zeta potenciálu častíc rovnakého druhu, z ELS spektra môžeme ...

The synthetic thermoplastic polymer polyetheretherketone (PEEK) is becoming a popular component of clinical orthopedic and spinal applications, but its practical use suffers from several limitations. Although PEEK is biocompatible, chemically stable, radiolucent and has an elastic modulus similar to that of normal human bone, it is biologically inert, preventing good integration with adjacent b...

This report documents treatment and repair of three carious teeth that were restored with a new dental repair material that features the characteristics of both resin-modified glass-ionomer restorative cement (RMGI) and resin-based composite (RBC). The restorative products presented are reported by the manufacturer to be the first bioactive dental materials with an ionic resin matrix, a shock-a...

Personalizing nutrition for cancer prevention and therapy will require a comprehensive understanding of "genotypes/phenotypes" in order to identify, evaluate, and prioritize appropriate points for dietary intervention. This nutritional preemption roadmap must begin with accurately assessing intakes/exposures of which bioactive food component(s) is needed to bring about a desired response in cri...

Airway mucins, the major component of airway mucus or apical surface fluid that covers the entire surface of the airways, have been shown to possess multi-factorial functions that are necessary for first line defense, the major function of airway mucus. In this mini-review, I will provide some evidence, both theoretical and experimental, that the multi-factorial functions of airway mucins are m...

India has rich history of using plants for medicinal purposes. Curcuma species are well-known indigenous medicine. They are used for the treatment of various ailments and metabolic disorders. In Manipur, traditionally the rhizomes of Curcuma caesia Roxb. is used in treating leucoderma, asthma, tumours, piles, bronchitis etc. The paste is applied on bruises, contusions and rheumatic pains. Essen...