In situ product recovery (ISPR), in the form of an extractive fermentation process, can increase productivity and titers sustainable production platform chemicals. To establish a guideline for development industrially relevant processes such bio-based compounds, wide screening was performed, mapping potential extensive range solvents solvent mixtures. Besides biocompatibility with Saccharomyces...

The review summarizes different bioinformatics tools used in studying the degradation of various xenobiotic compounds. Databases and Pathway Prediction Systems are key involved biodegradation. Several bio-degradative databases including EAWAG-BBD (Biocatalysis/Biodegradation Database), Plastics Microbial Biodegradation Database, ONDB (Organonitrogen Degradation Food risk component database (Foo...

Glycerine (glycerol) is a polyol consisting of three carbon atoms bonded to hydroxyl groups. It by-product the transesterification triglycerides, such as animal fats, vegetable oils, or used cooking oils during biodiesel production process. Crude glycerine subject purification processes resulting in distilled containing at least 99.5% glycerol. Currently, produced high-quality food, pharmaceuti...

The main monomer of tomato cuticle, 10,16-dihydroxyhexadecanoic acid (or 10,16-dihydroxypalmitic acid; 10,16-DHPA), was isolated and used to efficiently synthesize two different monomers (16-hydroxy-10-oxo-hexadecanoic and 7-oxohexa-decanedioic acids) in addition to a dimer and linear and branched trimers. These compounds were fully characterized using NMR and MS techniques and could be used as...

The UK Synthetic Biology Research Centre, SYNBIOCHEM, hosted by the Manchester Institute of Biotechnology at the University of Manchester is delivering innovative technology platforms to facilitate the predictable engineering of microbial bio-factories for fine and speciality chemicals production. We provide an overview of our foundry activities that are being applied to grand challenge project...

of chemical bonds but can also catalyze the radical-based re-polymerization of lignin fragments. In contrast, nonradical lignolytic enzymes selectively cleave chemical bonds in lignin and lignin model compounds and, thus, show promise for use in the preparation of high valueadded chemicals. In this mini-review, recent developments on non-radical lignolytic enzymes are discussed. These include r...

Research efforts to find more sustainable pathways for the synthesis of adipic acid have led to the introduction of new catalytic processes for producing this commodity chemical from alternative resources. With a focus on the performance of oxygen and hydrogen peroxide as preferred oxidants, this minireview summarizes recent advances made in the selective oxidation of cyclohexene, cyclohexane, ...

Glycerol hydrogenolysis represents one of the most promising technologies for future bio-refineries. In this context, kinetic modeling provides key quantitative assessment significance various reactions process development. However, as present, there are only limited studies on detailed glycerol conversion to 1,2-propanediol, ethylene glycol and other alcoholic products. work, a comprehensive s...

In the future, biomass will continue to emerge as a viable source of chemicals. The development of new industries that utilize bio-renewables provides opportunities for innovation. For example, bio- and chemo-catalysts can be combined in 'one pot' to prepare chemicals of commercial value. This has been demonstrated using isolated enzymes and whole cells for a variety of chemical transformations...

BACKGROUND Succinic acid is one of the key platform chemicals which can be produced via biotechnology process instead of petrochemical process. Biomass derived bio-oil have been investigated intensively as an alternative of diesel and gasoline fuels. Bio-oil could be fractionized into organic phase and aqueous phase parts. The organic phase bio-oil can be easily upgraded to transport fuel. The ...