Berberine has been used for the adjuvant treatment of type 2 diabetes mellitus, hyperlipidemia (high levels fats), and hypertension blood pressure). Also, it different effects on diarrhea, inflammation, cancer. Berberine, is a profoundly common compound in Berberis species. Although cretica one species, unknown whether anti-diabetic yet. synergistic various compounds together with berberin or s...

Drosophila melanogaster mutants with deficient kynurenine (KYN) formation from tryptophan (TRP) have longer life span than wild type flies. Administration of alpha-methyl-TRP and 5-methyl-TRY, the inhibitors of TRP-KYN metabolism, prolonged life span in wild-type flies. Both inhibitors are not available for human use. Berberine, an isoquinoline alkaloid isolated from Berberis aristata, is known...

The leading cause of cancer mortality globally amongst the women is due to human papillomavirus (HPV) infection. There is need to explore anti-cancerous drugs against this life-threatening infection. Traditionally, different natural compounds such as withaferin A, artemisinin, ursolic acid, ferulic acid, (-)-epigallocatechin-3-gallate, berberin, resveratrol, jaceosidin, curcumin, gingerol, indo...

Cigarette smoke-induced airway inflammationmucus over-production is one of the most important pathogenic features of chronic airway diseases. This study aimed to investigate the effect of berberine, a plant alkaloid with strong anti-inflammatory property, on cigarette smoke-induced airway inflammation and mucushypersecretion in mice. Mice with exposure to cigarette smoke wereintraperitonealy in...

Bergenin is a C-glucoside of 4-O-methyl gallic acid is a colourless crystalline polyphenol isolated from medicinal plants like Bergenial crassifolia (B. crassifolia), Mallotus philippinensis (M. philippinensis), Corylopsis spicata (C. spicata), Caesalpinia digyna (C. digyna), Mallotus japonicus (M. japonicus), Sacoglottis gabonensis (S. gabonensis) etc. It is hydrolyzable tannin and an isocouma...

An efficient protocol for hairy root induction in Berberis aristata DC. was established using two different strains of Agrobacterium rhizogenes, MTCC 532 and 2364 from IMTECH (Institute of Microbial Technology), Chandigarh, India. The strain 532 was more effective than strain 2364 in hairy root induction and in vitro grown callus (61.11 ± 1.60 % transformation frequency) was found to be suitabl...

Berberin được phân lập từ cây Coscinium fenestratum và một số trong họ Ranunculaceae có tác dụng chữa vết thương do bỏng. Nghiên cứu xác định độc tính bán cấp của gel nano Berberine Bệnh viện Bỏng Quốc gia sản xuất qua đường uống ở chuột cống trắng; theo mô hình OECD 423, 2008. Tiến hành trên 30 con chuột, chia thành 3 nhóm, nhóm thử liều 1 3,5g/1kg/24h, 2 10,5g/1kg/24h, chứng nước cất với 10,2...

Nizami Sırlar Hazinesi’ne adlı mesnevisinde folklor ürünlerini ve halk yaratıcılığını yaygın olarak kullanmıştır. Manevi ahlaki değerlere adanmış yirmi sohbetin kaleme aldığı hikayelerin neredeyse tamamında, arasında dolaşan efsane anlatılardan faydalanmıştır. Hazinesi, “Nuşiravan ile Baykuşların Sohbeti”, “Sultan Sencer Yaşlı Kadının Hikayesi”, “Bir Şehzadenin “Harnel Reşid Berberin Hikayesi” ...

INTRODUCTION Nutraceuticals (NUT) are forms of compounds with biological activity commonly used to improve health in dosage largely exceeding those obtainable in food. AIM We compared, in a double blind randomized cross-over trial, the effects of two NUT combinations on the control of glico-lipidic metabolism in patients with hypercholesterolemia not on statins. METHODS At study start patie...