In this paper we represent the work to improve the quality or reducing the effective BER in a multipath fading channel. BER is inversely proportional to SNR so high SNR results in low BER and vice versa. The study of this paper is to have focus on the performance of digital communication system. For reliable communication system, its BER should be as low as possible i.e. improvement in BER. BER...

Sepsis remains a major cause of mortality in intensive care units, better therapies are urgently needed. Gram-negative bacterial lipopolysaccharide (LPS) is an important trigger of sepsis. We have demonstrated that berberine (Ber) protects against lethality induced by LPS, which is enhanced by yohimbine (Y) pretreatment, and Ber combined with Y also improves survival in septic mice. However, th...

Base excision repair (BER) pathway executed by a complex network of proteins is the major system responsible for the removal of damaged DNA bases and repair of DNA single strand breaks (SSBs) generated by environmental agents, such as certain cancer therapies, or arising spontaneously during cellular metabolism. Both modified DNA bases and SSBs with ends other than 3'-OH and 5'-P are repaired e...

BACKGROUND Berberine (Ber), used widely as an antibacterial, antifungal, and anti-inflammatory drug, has long been used as a gastrointestinal remedy in Chinese traditional medicine. Recent reports have suggested that Ber suppresses Th17 responses that was mediated by direct actions on T cells and thymic stromal lymphopoietin production in primary mast cells. It has been suggested that Ber may b...

Berberine (Ber), an isoquinoline derivative alkaloid and active ingredient of Coptis, has been demonstrated to possess antidiabetic activities. However its low oral bioavailability restricts its clinical application. In this report, Ber nanosuspension (Ber-NS) composed of Ber and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) was prepared by high pressure homogenization technique. Ant...

Antibacterial activity of berberine (Ber) and 8-acetonyl-dihydroberberine (A-Ber) alone and combined uses with antibacterial agents ampicillin (AMP), azithromycin (AZM), cefazolin (CFZ) and levofloxacin (LEV) was studied on 10 clinical isolates of SCCmec III type methicillin-resistant Staphylococcus aureus (MRSA). Susceptibility to each agent alone was tested using a broth microdilution method ...

Base excision DNA repair (BER) is fundamentally important in handling diverse lesions produced as a result of the intrinsic instability of DNA or by various endogenous and exogenous reactive species. Defects in the BER process have been associated with cancer susceptibility and neurodegenerative disorders. BER funnels diverse base lesions into a common intermediate, apurinic/apyrimidinic (AP) s...

In this paper, by using some classical Mulholland type inequality, Berezin symbols and reproducing kernel technique, we prove the power inequalities for number $ber(A)$ self-adjoint operators $A$ on ${H}(\Omega )$. Namely, inequality Hilbert space are established. By applying that $(ber(A))^{n}\leq C_{1}ber(A^{n})$ any positive operator

This paper investigates the Multi-band OFDM (MB-OFDM) based physical (PHY) layer proposal for IEEE 802.15.3a working group on short-range high data-rate Ultra-wide-Band (UWB) communications. An overview of the MB-OFDM PHY layer architecture with its various parameters is presented and the optimal choice of critical parameters is discussed. Next, we derive the theoretical un-coded Bit Error Rate...