In the asymmetric unit of the title compound, C(16)H(11)FO(5)S, the 2H-chromene ring is essentially planar, with a maximum deviation of 0.040 (2) Å. The dihedral angle between the 2H-chromene ring and the 4-fluoro-phenyl ring is 2.17 (8)°. One of the sulfonamide O atoms is approximately coplanar with the benzene ring [C-C-S-O torsion angle = 166.00 (14)°], whereas the other O atom lies well bel...

In the title compound, C(23)H(25)BrN(4)O(3)S(2), the benzene rings bridged by the sulfonamide group are tilted relative to each other by 69.7 (1)° and the dihedral angle between the sulfur-bridged pyrimidine and benzene rings is 70.4 (1)°. The mol-ecular conformation is stabilized by a weak intra-molecular π-π stacking inter-action between the pyrimidine and the 4-methyl benzene rings [centroid...

The title mol-ecule, C(11)H(15)N(3)O(2)S, features a five-membered ring which is twisted about the middle CH(2)-CH(2) bond. The benzene ring is inclined with respect to the imine residue [C-N-N-C torsion angle = 165.4 (2)°]. Supra-molecular layers in the bc plane are formed by hydrogen bonds between the amine H atoms and sulfonamide O and imine N atoms, as well as by a weak hydrazine H-atom int...

Objectives: The objective of this endeavour is to prepare βcyclodextrin (β-CD) inclusion complex with sulfonamide (SAP) using the co-evaporation technique and screened its effect on in-vitro antimicrobial property against some Gram-positive and Gramnegative bacteria. Methods: A new sulfonamide SAP (4-amino-N-(1, 5-dimethyl-3oxo-2-phenyl-2, 3-dihydro-1H-pyrazol-4-yl) benzene sulfonamide) 4 has b...

Today Cancer remains to be one of the most deadly diseases in the world. Due to the potential anticancer activity of the chalcone and sulfonamide moieties, five novel hybrid compounds containing both structures have been designed and synthesized in 3 steps. The synthesized compounds were established on the basis of IR, 1H NMR, 13C NMR spectral data, and elemental analysis and also they were scr...

The title compound, C(15)H(21)N(3)O(3)S, is known to be an impurity of gliclazide [systematic name: N-(hexa-hydro-1H-cyclopenta[c]pyrrol-2-ylcarbamo-yl)-4-methyl-benzene-sulfonamide], a sul-fonyl-urea anti-diabetic drug. Gliclazide has a p-tolyl group substituting the sulfonamide functionality, while the title mol-ecule contains an o-tolyl group. Both five-membered fused rings adopt envelope co...

In the title compound, C(13)H(13)NO(3)S, the benzene ring of the benzene-sulfonamide moiety is disordered with an occupancy ratio of 0.56 (3):0.44 (3), the disorder components being twisted at and angle of 21 (1)° to each other. The meth-oxy-benzene group is roughly planar (r.m.s. deviation = 0.0144 Å) and the amide N atom is displaced from this plane by 0.090 (6) Å. The dihedral angles between...

The structure of the title sulfonamide, C(12)H(15)Cl(2)NO(2)S, features a distorted tetra-hedral geometry for the S atom [maximum deviation: O-S-O = 120.23 (14)°]. One of the sulfonamide O atoms is coplanar with the benzene ring [C-C-S-O torsion angle = -174.5 (2)°], whereas the other lies well above the plane [C-C-S-O = 57.0 (3)°]. A chair conformation is found for the cyclo-hexyl ring. In the...

The title compound, C23H22N2O2S, crystallizes with the 4-methyl-benzene-sulfonamide entity oriented towards the center of the bridgehead C atoms with a C-N-S-C torsion angle of -61.3 (2)°. The mol-ecule features an intra-molecular N-H⋯N hydrogen bond. Weak C-H⋯O and C-H⋯π inter-actions aid in forming the three-dimensional supra-molecular structure.

The title compound, C(15)H(21)NO(2)S, synthesized by N-alkyl-ation of cyclo-hexyl-amine benzene-sulfonamide with allyl iodide, is of inter-est as a precursor to biologically active sulfur-containing heterocyclic compounds. The cyclo-hexane ring is in a chair form and its mean plane makes a dihedral angle of 53.84 (12)° with the phenyl ring.