This manuscript reviews the recent progress on mesoporous silica nanoparticles as drug delivery systems. Their intrinsic structural, textural and chemical features permit to design versatile multifunctional nanosystems with the capability to target the diseased tissue and release the cargo on demand upon exposition to internal or external stimuli. The degradation rate of these nanocarriers in d...

In traditional IT outsourcing and multisourcing arrangements, clients isolate vendor tasks, resulting in modular sourcing structures. But this approach can stifle vendor competition, result in vendor lock-in and hinder organizational flexibility. The full article describes how adidas adopted a new type of multisourcing strategy, which embraces vendor overlaps to overcome these constraints, and ...

First call resolution, which in essence means the proportion of inquires that are successfully addressed after one call (note that the definitions of FCR differ, see below), has been getting more attention in call center management. A review of the literature, however, reveals that most of the interest has come from the practitioners (call center managers, consultants, etc.). We can only find a...

Posttraumatic thumb defects result in significant functional impairment. Multiple reconstructive procedures have been described for the management and improvement of function. Compared with no treatment, all methods are beneficial. Each available may be more applicable under certain conditions, can offer great benefits, its own downsides as well. With a thorough assessment meticulous technique,...