to assess the association between polymorphisms of the il-6 -174 g/c and behçet's disease (bd) in tunisian patients. dna was extracted from blood samples taken from 43 tunisian patients and 43 healthy controls. the polymorphisms were analyzed by pcr with the pcr-rflp. no significant association was found between patients and controls concerning polymorphism of il6 -174 g/c between the (allelic ...

behcet's disease (bd) is a multisystemic inflammatory disease that occurs most often between the second and fourth decade of life. patients have been reported during the first months of life and after 70 years. our objective was to determine the clinical, paraclinical and genetic characteristics of bd in patients aged < 20 and > 40 years. we conducted a comparative retrospective study including...

purpose: to evaluate the distribution of tnf-alpha promoter -1031t/c and -308g/a polymorphisms in an iranian population with behcet disease and ocular manifestation. method: we investigated the distribution of tnf-alpha promoter -1031t/c and -308g/a polymorphisms in 53 patients with behcet disease (bd) and 79 matched healthy controls, using the pcr-rflp technique. all subjects were from an iran...

introduction: behcet&apos;s disease is a chronic disease with multisystem involvement characterized clinically by oral and genital aphthae, cutaneous lesions and ophthalmologic, neurologic and gastrointestinal manifestation. nervous system involvement occurs in 5.3 – 30% of patients, mostly in brain stem and basal ganglia. the common manifestations are pyramidal signs, central nervous plegia, p...

background: this study was designed to determine and compare the stress, anxiety and depression levels in behcet’s disease (bd) patients and a control group of normal individuals. materials and methods: one-hundred and six patients with bd were selected as cases and controls were 106 age- and sex-matched participants referred to the shiraz dental school clinics due to dental problems. we collec...

Behçet disease is a multisystem disease of unknown cause in which an inflammatory perivasculitis can arise in almost any tissue (Sakane et al., 1999). Neurologic involvement in Behçet disease was first reported by Knapp in 1941. It represented between 4-49% of manifestations of BD (Haghighi et al., 2005). There is one of the most serious causes of long term morbidity and mortality in Behçet’s D...

Behçet's disease (BD), also known as the Silk Road disease, is a multisystemic and rare inflammatory disorder primarily prevalent in populations along the Mediterranean Sea. Today, BD is defined as a crossroad between autoimmune and auto-inflammatory syndromes. Variety of syndromes including mucocutaneous manifestations such as oral and genital ulcers, papulopustular lesions and erythema nodosu...