Central nervous system involvement in Behçet disease (BD) may be either parenchymal or nonparenchymal. Abnormal cerebrospinal fluid findings and parenchymal involvement are associated with a poorer prognosis. A self-antigenic role for HLA B51 has been postulated in the pathogenesis of BD. The sibling occurrence rate is 3.6%. Familial aggregation may be more pronounced among pediatric cases comp...

BACKGROUND To evaluate therapeutic outcomes of interferon alpha-2a (IFNα2a) treatment in patients with Behcet's disease who were refractory to immunosuppressive agents. METHODS This retrospective case series reviewed the medical records of 5 patients with refractory Behcet uveitis from January 2011 to February 2017. IFNα2a was administered at a dose of 3 million IU 3 times per week. Clinical ...

Aneurysm or pseudoaneurysm formation is one of the vascular complications of Behcet disease. At present, the optimal treatment for the disease has not been established.The authors report a case of vasculo-Behcet disease (v-BD) with recurrent pseudoaneurysms in the left infrainguinal arteries (common femoral artery, superficial femoral artery, and popliteal artery), as well as thrombosis in the ...

background the behcet disease is a multisystemic disease with involvement of vessels. objectives our aim is to evaluate the frequency of carotid artery disease in asymptomatic carotid artery involvement in patients with behcet disease and compare the results with a control group. patients and methods fifty patients with behcet disease who were asymptomatic for any vascular involvement and 50 he...

large vessel involvement is one of the hallmarks of behcet’s disease (bd) but its prevalence varies widely due to ethnic variation or environmental factors. the aim of this study is to find the characteristics of vasculo-behcet (vb) in iran. in a cohort of 4769 patients with bd, those with vascular involvement were selected. different manifestations of disease were compared with the remaining g...