Background: Therapeutic hypothermia has become an established protocol for all neonates with moderate to severe Hypoxic Ischaemic Encephalopathy (HIE). There are very few studies comparing the neurodevelopmental outcomes in asphyxiated neonates who received therapeutic hypothermia or did not. This study aimed to assess the neurodevelopmental outcomes of asphyxiated neonates with features of HIE...

BACKGROUND This study was conducted to find out whether boys with constitutional delay in growth and puberty (CDGP) could attain their target height and predicted adult height (PAH) in adulthood or not. METHODS After measuring the height, weight, pubertal stage, parental height and bone age data of the patients at their first presentation were extracted from the files and their height and wei...

In low- and middle-income countries (LIMCs), measuring early childhood development (ECD) with standard tests in large scale surveys and evaluations of interventions is difficult and expensive. Multi-dimensional screeners and single-domain tests ('short tests') are frequently used as alternatives. However, their validity in these circumstances is unknown. We examined the feasibility, reliability...

BACKGROUND In Nigeria and sub-Saharan Africa at large, there has been heavy reliance on the "Caucasian data" in the developmental assessment of children. Hence, this study set out to establish normative data for psychomotor development on Nigerian children. STUDY DESIGN One hundred and twenty eight children distributed equally to eight different integrative age groups between 8 weeks and 30 m...

This study evaluates the neurodevelopment of children living near contaminated mining industries during their first year of life. Participants from the city of Oruro (Bolivia) were prospectively recruited during pregnancy. Follow-up occurred between May 2007 and November 2009. Information about the socioeconomic status and medical history of the pregnant women were collected using questionnaire...

BACKGROUND Different structural and non-structural models have been used to describe human growth patterns. However, few studies have compared the fitness of these models in an African transitioning population. AIM To find model(s) that best describe the growth pattern from birth to early childhood using mixed effect modelling. SUBJECTS AND METHODS The study compared the fitness of four str...

Objective To identify the usefulness of both the Bayley Scales of Infant and Toddler Development, 3rd edition (Bayley-III) and Denver Developmental Screening Test II (DDST-II) in preterm babies with neurodevelopmental impairment, considering the detection rate as regulation of criteria. Methods Retrospective medical chart reviews which included the Bayley-III and DDST-II, were conducted for 6...

The goal of this study is to assess whether a growth curve model approach will lead to a more precise detection of Turner sydnrome (TS) than conventional referral criteria for growth monitoring. The Jenss-Bayley growth curve model was used to describe the process of growth over time. A new screening rule is defined on the parameters of this growth curve model, parental height and gestational ag...

BACKGROUND There is a need for valid and reliable observational measures of early child development in low-income and middle-income country settings. METHODS The aims of the study were to adapt the Bayley Scales of Infant Development (Bayley III) for a rural Ethiopian setting and evaluate reliability and validity. The study was carried out between January 2008 and January 2009 in the Butajira...

The aim of this study was to follow-up infants who were assessed in early infancy, at approximately 6 months of age, to determine the developmental impact of social withdrawal at approximately 30 months of age. Infants were administered the Bayley Scales of Infant Development-Third Edition, and the mothers complete the Behavior Assessment System for Children (BASC), Second Edition-Parent Rating...