We engineered nanomedicine with the stealth corona made up of densely packed bone seeking ligand, alendronic acid. In a typical nanoconstruct, alendronic acid is conjugated with hydrophilic head moiety of phospholipid that has an ability to self-assemble with hydrophobic polymeric core through its hydrophobic long carbon-chain. Proposed nanomedicine has three distinct compartments namely; poly(...

‘nanomedicine.’’ Nanomedicine -delivery systems are of great scientific interest and give hope for treatments for heart disease, diabetes and other diseases. Many novel e in diagnostic and treatment

aptamers define a new interesting class of receptor molecules with capability of binding to potentially any kind of molecules of interest. structurally, they are composed of nucleic acids (rna, dna or a mixture of both) with high specificity and affinity to amino acids, drugs, proteins and other molecules. apatmers are isolated from complex libraries of synthetic nucleic acids against the desir...

cerebral palsy (cp) is the most common motor disability in children, usually occurring during fetal development; before, during, or shortly after birth, or during infancy. cp takes place in about 2.1 per 1,000 live births .there is no exact reason but birth injury or inflammation of the central nervous system, infections and hypoxia are related risk factors of this disease. often, symptoms incl...

Fucoidans are widespread cost-effective sulfated marine polysaccharides which have raised interest in the scientific community over last decades for their wide spectrum of bioactivities. Unsurprisingly, nanomedicine has grasped these compounds to develop innovative therapeutic and diagnostic nanosystems. The applications of fucoidans in nanomedicine as imaging agents, drug carriers or for their...

This handbook volume is part of the Reference Series: Micro/Nano Technologies. individual provides a comprehensive, self-contained, and ...

Welcome to the international journey to improving human health It is with great excitement that I welcome you to the International Journal of Nanomedicine (IJN). This new journal has been launched to bring you the latest, exciting, up-to-date research conducted at the intersection of nanotechnology and medicine. As you will see in this issue alone, researchers from around the world are actively...

An accurate characterization of nanomaterials used in clinical diagnosis and therapeutics is of paramount importance to realize the full potential of nanotechnology in medicine and to avoid unexpected and potentially harmful toxic effects due to these materials. A number of technical modalities are currently in use to study the physical, chemical and biological properties of nanomaterials but t...

Effective delivery of nanomedicines to tumor tissues depends on both the tumor microenvironment and nanomedicine properties. Accordingly, tumor microenvironment modification or advanced design of nanomedicine was emerging to improve nanomedicine delivery to tumors. However, few studies have emphasized the necessity to optimize the tumor microenvironment and nanomedicine properties simultaneousl...