Department of Ophthalmology, Sir Run Run Shaw Hospital, Zhejiang Univ Abbreviations and Acronyms: CDS 1⁄4 Cornea Donor Study; DMEK 1⁄4 Descemet membrane endothelial keratoplasty; DSEK 1⁄4 Descemet stripping endothelial keratoplasty; ECD 1⁄4 endothelial cell density; EK 1⁄4 endothelial keratoplasty; FECD 1⁄4 Fuchs’ endothelial corneal dystrophy; MCMC 1⁄4 Markov chain Monte Carlo; PACE 1⁄4 pseudo...

We used a surgical technique that combines deep lamellar keratoplasty, phacoemulsification, and intraocular lens implantation for treating patients with cataract and corneal stromal disease. Deep lamellar dissection of the cornea was first performed with viscoelastic substances (hyaluronate sodium) until the highly transparent Descemet membrane solely remained. We then created a short corneal t...

OBJECTIVE To evaluate Descemet membrane endothelial keratoplasty for management of corneal endothelial disorders. METHODS Descemet membrane endothelial keratoplasty was performed in 200 patients with Fuchs endothelial dystrophy or bullous keratopathy. Best-corrected visual acuity, subjective and objective refractive outcome and stability, and endothelial cell density were evaluated at 1, 3, a...

Endothelial keratoplasty is now favored over full-thickness penetrating keratoplasty for corneal decompensation secondary to endothelial dysfunction. Although endothelial keratoplasty has evolved as surgeons strive to improve outcomes, fewer patients than expected achieve best corrected visual acuity of 20/20 despite healthy grafts and no ocular comorbidities. Reasons for this remain unclear, w...

ReportofaCase.A71-year-oldwhitewomanwithan8-year history of refractory multiple myeloma had blurred vision. Herbest-correctedvisualacuitywas20/30OU.Inbotheyes, the cornea manifested a remarkable golden-brown, metallic sheen that on slitlamp examination was determined to be at the level of the Descemet membrane (Figure1). The remainder of her examination disclosed no abnormalities. Several month...

The objective of this study was to characterize the proteome of the corneal endothelial cell layer and its basement membrane (Descemet membrane) in humans with various severities of type II diabetes mellitus compared to controls, and identify differentially expressed proteins across a range of diabetic disease severities that may influence corneal endothelial cell health. Endothelium-Descemet m...

DEEP ANTERIOR LAMELLAR KERATOPLASTY: A NEW MANUAL TECHNIQUE Rama et al report visual outcomes in 288 eyes undergoing deep anterior lamellar keratoplasty with a new manual dissection technique. A deep corneal incision was obtained with a calibrated diamond knife to reach a pre-Descemet plane. At the 2-year postoperative follow-up, the mean logarithm of the minimum angle of resolution best specta...

To the Editor: Descemet detachment in cataract surgery can compromise visual results and implicate the need for more surgical procedures.1 Since 2009, when femtosecond laserassisted cataract surgery (FLACS) was first introduced, only one case of Descemet detachment has been reported in a study assessing intraoperative complication rates, and it is not clear whether the detachment was caused by ...

Mycetomas are a chronic skin infection characterized by perilesional edema, formation of sinus tracts, and discharge of purulent or seropurulent exudate containing grains. This report aims to demonstrate the clinical diagnosis (by dermoscopy) of a skin lesion that initially bared no clinical features of a mycetoma.