The transition from a Drosophila ovarian germline stem cell (GSC) to its differentiated daughter cell, the cystoblast, is controlled by both niche signals and intrinsic factors. piwi and pumilio (pum) are essential for GSC self-renewal, whereas bag-of-marbles (bam) is required for cystoblast differentiation. We demonstrate that Piwi and Bam proteins are expressed independently of each other in ...

Background: With regard to the perceptible population, cultural, social and environmental changes in the aftermath of the earthquake in Bam City, this study was conducted to pinpoint substance misuse patterns and to figure out the probable relationship between substance misuse and blood types of the addicts referred to Substance rehabilitation Clinics from 2006 to 2007 in Bam City. Methods: In ...

The Drosophila germ-cell lineage has emerged as a remarkable system for identifying genes required for changes in cell fate from stem cells into more specialized cells. Previous work indicates that bam expression is necessary for cystoblast differentiation; bam mutant germ cells fail to differentiate, but instead proliferate like stem cells. This paper reports that ectopic expression of bam is ...

Bag of Marbles (Bam) is a stem cell differentiation factor in the Drosophila germ line. Here, we demonstrate that Bam has a crucial function in the lymph gland, the tissue that orchestrates the second phase of Drosophila hematopoiesis. In bam mutant larvae, depletion of hematopoietic progenitors is observed, coupled with prodigious production of differentiated hemocytes. Conversely, forced expr...

disasters provide physical, social, political and environmental development windows of opportunities that can be used not only to reconstruct the impacted areas, but also to improve the socio-economic and physical conditions of the impacted population in the long run. it is argued, however, that there is a limited time frame of approximately four years for such opportunities to be utilized effi...

Bag of Marbles (Bam) is known to function as a positive regulator of hematopoietic progenitor maintenance in the lymph gland blood cell-forming organ during Drosophila hematopoiesis. Here, we demonstrate a key function for Bam in cells of the lymph gland posterior signaling center (PSC), a cellular domain proven to function as a hematopoietic niche. Bam is expressed in PSC cells, and gene loss-...

The Rsamtools package provides an interface to BAM files. BAM files are produced by samtools and other software, and represent a flexible format for storing ‘short’ reads aligned to reference genomes. BAM files typically contain sequence and base qualities, and alignment coordinates and quality measures. BAM files are appealing for several reasons. The format is flexible enough to represent rea...

BACKGROUND To examine factors predicting type of bladder antimuscarinics (BAM) initiated in nursing home (NH) residents. METHODS Incident BAM initiators following NH admission were identified by constructing a retrospective cohort from Medicare files and Minimum Data Set (MDS). Participants included all residents 65 years and older admitted in Medicare-certified NH between January 1, 2007 and...

Natural disasters in various forms have been identified as destructive phenomena during the life of earth planet and are also a serious threat to the inhabitants of the planet. Therefore, this issue leaded to the formation of a process called crisis management which includes activities occurring before, within and after the event to reduce the vulnerability. The country of Iran is considered as...