The Center for Transportation Research (CTR) Vehicle Systems team modified a Nissan CK-2 Continuously Variable Transmission (CVT) for a diesel hybrid powertrain application. Mechanical and electrical modifications were made to the CVT, both internal and external to the transmission. The goal of this experiment was to investigate and demonstrate the potential of CVT for diesel engines hybrid ele...

Cerebral venous and dural sinus thrombosis (CVT) is a rare condition with a wide spectrum of clinical presentations. The epidemiology of the disease has evolved considerably during the recent decades with increasing oral contraceptive use in young and middle-aged women. CVT has various causes including genetic and acquired prothrombotic disorders and it usually has a favorable outcome with a lo...

BACKGROUND AND PURPOSE After cerebral vein and dural sinus thrombosis (CVT), there is an increased risk of further venous thromboembolic events (VTEs). Time to a second cerebral or systemic venous thrombotic event and risk factors for recurrence have not been investigated in large prospective studies. METHODS We used the International Study on Cerebral Vein and Dural sinus Thrombosis, which i...

Cerebral venous thrombosis (CVT) and deep vein thrombosis or pulmonary embolism (DVT/PE) are associated with many risk factors. It is unclear why CVT occurs less often than DVT/PE. Age dependent risk factors may play a role. The aim of our study was to compare risk factors in a uniform age group of CVT and DVT/PE patients aged between 15 and 50 years. Thrombophilic markers and clinical risk fac...

Revolute-jointed cobots depend on continuously variable transmissions (CVTs). CVTs constrain the speed ratio between two shafts to a particular value within a continuous range. The spherical CVT is well suited to cobots, but like other point contact transmissions, achieving good performance is challenging. We have studied the contact mechanics of the spherical CVT under certain simplifying assu...

Aminopeptidase I (API) is imported into the yeast vacuole/lysosome by a constitutive non-classical vesicular transport mechanism, the cytoplasm to vacuole targeting (Cvt) pathway. Newly synthesized precursor API is sequestered in double-membrane cytoplasmic Cvt vesicles. The Cvt vesicles fuse with the vacuole, releasing single-membrane Cvt bodies containing proAPI into the vacuolar lumen, and m...

Cerebral venous thrombosis (CVT) is a challenging condition because of the variability of clinical presentations. CVT can present at all ages, but is seen more in young and middle-aged women. CVT does not necessarily occur only when there is an obvious underlying etiology. In almost 30% of cases, the etiology cannot be established. CVT can present with an acute thunderclap headache, fever, seiz...

BACKGROUND Patients with isolated headache may have cerebral venous thrombosis (CVT). D-dimers are proven sensitive in excluding deep venous thrombosis (DVT) and pulmonary embolism (PE) in low risk patients. We aimed to determine whether D-dimer may play the same role in low risk CVT patients with isolated headache. METHODS We included consecutive patients suspected of CVT from our teaching h...

BACKGROUND Cerebral venous thrombosis (CVT) is a distinct disorder with highly variable symptoms and courses. Malignancy is known to be one of the predisposing factors of CVT. CASE REPORT We present the case of a 69-year-old man with sudden behavioral changes. Brain MRI, magnetic resonance venography, and positive D-dimer assay confirmed the presence of CVT. The work-up for detecting the caus...

Cerebral venous thrombosis (CVT) is a clinical condition which is caused by the partial or complete occlusion of the dural sinuses and cerebral veins. Cases of associated CVT and multiple sclerosis (MS) have been reported and CVT development has been attributed to the previous lumbar puncture (LP) in majority of these cases. We report a case of 32-year-old woman with no previous history of rece...