4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB was employed in the presence of a weak anion exchange resin to perform dynamic kinetic resolutions of racemic benzyl ketones with high conversions and good optical purities. Different parameters that affect to the efficiency of the enzymatic Baeyer-Villiger oxidation and racemisation were analyzed in order to optimize the acti...

; originally published online October 4, 2010; 2010;126;e1168 Pediatrics Deborah Tomlinson, Carl L. von Baeyer, Jennifer N. Stinson and Lillian Sung Children A Systematic Review of Faces Scales for the Self-report of Pain Intensity in http://pediatrics.aappublications.org/content/126/5/e1168.full.html located on the World Wide Web at: The online version of this article, along with updated infor...

Baeyer–Villiger monooxygenases (BVMOs) are flavin-dependent oxidative enzymes capable of catalyzing the insertion an oxygen atom between a carbonylic Csp2 and Csp3 at alpha position, therefore transforming linear cyclic ketones into esters lactones. These dependent on nicotinamides (NAD(P)H) for flavin reduction subsequent reaction with molecular oxygen. BVMOs can be included in cascade reactio...

A Ser105Ala mutant of the lipase B from Candida antarctica enables 'perhydrolase-only' reactions. At the example of the chemoenzymatic Baeyer-Villiger oxidation of cyclohexanone, we demonstrate that with this mutant selective oxidation can be achieved in deep eutectic solvent while essentially eliminating the undesired hydrolysis reaction of the product.

The facile conversion of M-R to M-OR that could be useful for the functionalization of electron-rich metal alkyl intermediates is shown to proceed via a Baeyer-Villiger-type pathway involving a nonredox, electrophilic, O-atom insertion in reactions with non-peroxo O-donors.