BACKGROUND Meningococcal factor H binding protein (fHbp) is a promising vaccine candidate. Anti-fHbp antibodies can bind to meningococci and elicit complement-mediated bactericidal activity directly. The antibodies also can block binding of the human complement down-regulator, factor H (fH). Without bound fH, the organism would be expected to have increased susceptibility to bacteriolysis. Here...

propolis has traditionally been used in curing infections and healing wounds and burns. current researches have shown that propolis has antibacterial, antifungal and antiviral actions however, the pharmacological activity of propolis is highly variable depending on its geographic origin. there have been few studies on the effects of iranian propolis on the oral microorganisms. in this in-vitro ...

The bactericidal effects of chloramphenicol and three beta-lactams (ampicillin, cefamandole, and penicillin G) were measured for 27 strains of Haemophilus influenzae type b isolated from the blood or cerebrospinal fluid of infected infants. Of the ampicillin-susceptible strains, 75% were killed by less than 2.0 micrograms of each antibiotic per ml; however, the concentration of the beta-lactam ...

objective: this study aims to evaluate the antimicrobial activity, phytochemical studies and thin layer chromatography analysis of machine oil, hexane extract of seed oil and methanol extract of presscake& latex of jatropha curcas linn (family euphorbiaceae). materials and methods: j. curcas extracts were subjected to preliminary qualitative phytochemical screening to detect the major phytochem...

conclusions: despite the good in vitro bactericidal effect of amoxicillin on spiral forms of h. pylori, this antibiotic has little effect on induced coccoids that may develop after the inappropriate in vivo antibacterial treatment. hence, for successful therapy, it is essential not only to eradicate the spiral forms, but to eliminate the viable coccoids. background: helicobacter pylori (h. pylo...

In order to investigate the bactericidal effect of plaunotol, an oily antiulcer agent, against Helicobacter pylori, comparative studies were conducted using its derivatives, M-4, M-5, and M-6, whose hydrophobicity decreased in the order of plaunotol > M-6 > M-5 > M-4 by log P determination. Plaunotol rapidly reduced the viability of H. pylori in vitro, and cell death was associated with cell ly...

Introduction of silver into some inorganic material causes the resulting mixture to have antibacterial activity. Here, we investigated the role of silver in the bactericidal activity of silver-loaded zeolite, by measuring the effects of silverloaded zeolite on Escherichia coli cell viability under conditions in which the oxidation state of the silver was controlled electrochemically. Bactericid...

BACKGROUND Ultraviolet (UV) light is used for phototherapy in dermatology, and UVB light (around 310 nm) is effective for treatment of psoriasis and atopic dermatitis. In addition, it is known that UVC light (around 265 nm) has a bactericidal effect, but little is known about the bactericidal effect of UVB light. In this study, we examined the bactericidal effects of UVB-light emitting diode (L...

1. The bactericidal action of a number of anionic and cationic synthetic detergents on four Gram-positive and three Gram-negative bacteria has been investigated. 2. Cationic detergents, as a group, were found to exhibit marked bactericidal effects on Gram-positive microorganisms and somewhat less pronounced action on Gram-negative organisms. 3. The anionic detergents were germicidal only agains...