Before the nature of “bound” pantothenic acid was established, McIlwain and Hughes (1) showed that incubation of pantothenic acid with various streptococci or Proteus morganii led to its “inactivation” as a growth factor for these organisms. This inactivation reaction was dependent upon glycolysis, but independent of growth and the presence of oxygen, and was inhibited by pantoyltaurine (2). Mc...

The present study was conducted for the determination of physicochemical and microbial quality changes non-sulfited sun dried apricots (NSDAs) with three various moisture contents (MCs); 137 g/kg (MC137), 235 (MC235), 270 (MC270); at different temperatures (4, 10, 20, 30°C) during 12 months in bulk packaged storage. NSDAs were subjected to physical (moisture, water activity, pH reflectance colo...

Before the nature of “bound” pantothenic acid was established, McIlwain and Hughes (1) showed that incubation of pantothenic acid with various streptococci or Proteus morganii led to its “inactivation” as a growth factor for these organisms. This inactivation reaction was dependent upon glycolysis, but independent of growth and the presence of oxygen, and was inhibited by pantoyltaurine (2). Mc...

Childrenwith Helicobacter infection need treatment. The aim of treatment is elimination of H.Pylori. Most patients with this infection are asymptomatic and without peptic disease. Treatment and management of these patients are controversy. Conventional Treatment: The best treatment for H. pylori eradication regimens should have cure rates of at least 80%, be without major side effects, and indu...

childrenwith helicobacter infection need treatment. the aim of treatment is elimination of h.pylori. most patients with this infection are asymptomatic and without peptic disease. treatment and management of these patients are controversy. conventional treatment: the best treatment for h. pylori eradication regimens should have cure rates of at least 80%, be without major side effects, and indu...

A large series of publications 1-9 has proposed that cationic peptides from leukocytes kill bacteria primarily by causing a depolarization of their membranes leading to enhanced permeability. One group of cationic peptides from human neutrophils was even coined bacteri-cidal/permeability-increasing proteins. 3 Surprisingly, however, none of a large series of other publications that had proposed...

W hen it was first discovered, RNA was thought to have just one job in the cell: that of a messenger carrying the genetic instructions for protein synthesis to the ribosomes. But, since then, different RNA species have been shown to be key to the construction (1) and function of the ribosomal machinery and to control both the spliced state and levels of messenger RNAs (2–4). Right from the star...

The study of biological motility has been one of the key areas of biophysics for the past 30 years. Understanding mechanico-chemical transduction-how macromol-ecules and macromolecular complexes convert chemical energy to the production of force-has been seen as one of the essential goals of those seeking a physical understanding of life at the molecular level. The main focus of motility studie...

To the Editor—In an article recently published in the Journal, Lopez-Rojas et al [1] demonstrated that an in vitro mutant of Acinetobacter baumannii resistant to colistin had reduced in vivo fitness and decreased virulence, in terms of both mortality and survival, in a mouse model of peritoneal sepsis. They suggest that the lower in vivo bacterial fitness and decreased virulence of this mutant ...