we have reviewed the medical records of 40 patients with disseminated (bacille calmette-guerin) bcg from 1996 to 1999 in the immunology department of the children hospital, medical center, tehran university. these patients are divided in to 3 groups: 1. patients who had disseminated (bacille calmette-guerin) bcg after vaccination and their diagnosis was chronic granulomatous disease. 2. patient...

As a treatment for superficial transitional cell carcinoma, Bacillus Calmette-Guerin (BCG) intravesical instillation can rarely cause unpredictable systemic side effects. We describe a patient admitted due to continuous pyrexia and general fatigue. He was previously treated with intravesical BCG. Laboratory data indicated a hepatic disorder, and chest computed tomography revealed extensive bila...

For more than 70 years, Bacillus Calmette-Guerin (BCG) vaccines have been administered safely to billions of individuals throughout the world. Local adverse reactions following BCG vaccination usually occur at a rate of 0.1 to 0.5 per 1000 vaccinations, and serious, disseminated complications occur at a rate of less than 1 in a million vaccinations [1]. Physicians should be aware of the various...

despite the long history of the worldwide use of bacillus calmette-guerin (bcg) vaccine, a wide spectrum of adverse reactions has been observed in a small proportion of immunized infants; the most severe complication, disseminated bcgitis, is often fatal but exceedingly rare and is considered to result from host immunodeficiency. at present, ct scan, ultrasound, x-ray and bone marrow aspiration...

Received October 2006 Accepted March 2007 INTRODUCTION Intravesical instillation of bacillus Calmette-Guerin (BCG) is a known treatment method in superficial bladder cancers after transurethral resection of the bladder tumor (TURBT).(1) Moreover, its polysaccharide nucleotide is used in the treatment of asthma.(2) However, the most familiar usage of the BCG to the public is vaccination against ...

Approximately 70% of bladder transitional epithelium cell carcinomas are non-invasive muscular bladder cancers, and for the treatment and prevention of recurrence of this type of cancer, Bacillus Calmette-Guerin (BCG) is applied prophylactically. This practice is generally considered reliable and rarely causes systemic complications. We present here a case in which the patient underwent transur...

Henoch Schönlein purpura (HSP), also known as IgA vasculitis (IgAV), is a systemic small-vessel vasculitis that predominantly affects adolescents and is rare in adults. In many cases, the onset of HSP has been causally linked to an infectious disease. We encountered a case of HSP with severe renal involvement diagnosed by renal biopsy following bacillus Calmette-Guerin (BCG) therapy for bladder...

Treatment options for patients with non-muscle invasive bladder cancer (NMIBC) refractory to intravesical bacillus Calmette-Guerin (BCG) therapy is reviewed in this article based on the recent published literature. Although intravesical BCG is the best bladder sparing treatment option for NMIBC to prevent recurrence and progression, about 1/3 of cases are refractory to this treatment. At this p...

Bacillus Calmette-Guerin (BCG) therapy has been proven to be effective treatment for superficial bladder carcinoma with complications that are usually minor and self limited. Although rare, granulomatous hepatitis can develop, and it is important to recognize it and treat it promptly. The hepatitis which occurs appears to be the result of a hypersensitivity reaction to antigens present in the B...