نتایج جستجو برای: baba2

تعداد نتایج: 92  

Journal: :Cancer research 2001
C Prinz M Schöniger R Rad I Becker E Keiditsch S Wagenpfeil M Classen T Rösch W Schepp M Gerhard

Helicobacter pylori has been assigned as a class I carcinogen because of its relation to gastric adenocarcinoma. Chronic H. pylori infection may lead to severe gastritis, glandular atrophy (AT), and intestinal metaplasia (IM). Strains secreting the vacuolating toxin VacA and producing the cytotoxin-associated antigen CagA (type 1 strains), as well as the blood group antigen binding adhesin (Bab...

2011
A. Saxena S. Shukla K.N. Prasad U.C. Ghoshal

BACKGROUND & OBJECTIVES Certain genotype(s) of Helicobacter pylori strains may play important role in the development of gastric cancer (GC) and peptic ulcer disease (PUD). This study was undertaken to investigate the association of cagA, cagA3/ region subtypes, babA2 and vacA genotypes of H. pylori with GC, PUD and non-ulcer dyspepsia (NUD) as there are no such studies from India. METHODS A ...

2012
Gokben Ozbey Cem Aygun

There is not much information available regarding the prevalence of the genotypes of Helicobacter pylori isolates in Turkey, particularly in eastern Turkey. The aims of this study were to detect the prevalence of different genotypes of H. pylori in Turkish patients with gastrointestinal complaints and to determine the relationship of these genotypes with clinical outcome and sex. One hundred fo...

2017
Fehmida Bibi Sana Akhtar Alvi Sara Ali Sawan Muhammad Yasir Ali Sawan Asif A. Jiman-Fatani Esam I. Azhar

BACKGROUND AND OBJECTIVES Helicobacter pylori (H. pylori) infection is cause of several gastrointestinal diseases in humans. Virulence genes of H. pylori are associated with severity of disease and vary geographically. The aim of present study was to detect H. pylori in formalin-fixed paraffin-embedded (FFPE) tissues and further investigate prevalence of babA2, cagA, iceA1, iceA2, vacA s1/s2 an...

ژورنال: :مجله علمی دانشگاه علوم پزشکی گرگان 0
خاتون حیدری heidari kh رامین آذرهوش azarhoush r گرگان، خیابان پنجم آذر، مرکز آموزشی درمانی پنجم آذر، گروه پاتولوژی، تلفن 2220561-0171 ، نمابر 2227910 مهدی فرقاتی فر forghanifar m

زمینه و هدف : هلیکوباکترپیلوری از مهم ترین پاتوژن های معده در انسان است. حضور ژن های baba2 و hsp در اتصال به سلول های اپیتلیال معده و بیماری زایی باکتری نقش دارد. این مطالعه به منظور تعیین فراوانی ژن های baba2 و hsp در سویه های هلیکوباکترپیلوری جدا شده از بیماران مبتلا به اختلالات گوارشی انجام شد. روش بررسی : این مطالعه توصیفی – تحلیلی روی 80 بیمار با اختلالات گوارشی مراجعه کننده به مرکز آموزشی...

Background & Aims: Helicobacter pylori is a microaerophilic gram negative bacillus which is one of the most common human infections. This bacterium is associated with various diseases and having multiple virulence genes such as toxins and adhesion factors. Several adhesion factors of bacteria involved in binding to the gastric epithelial cell and cause infection. The purposes of this study were...

Journal: :medical laboratory journal 0
khatoon heydari islamic azad university of damghan, iran razmin azarhoosh faculty of medicine, golestan university of medical sciences, iran vahideh kazeminejhad faculty of medicine, golestan university of medical sciences, iran fatemeh shakeri faculty of medicine, golestan university of medical sciences, iran alireza noroozi 5th azar hospital, golestan university of medical sciences, iran

abstract       background and objective: baba2 and hpa genes are involved in adherence of helicobacter pylori (h.pylori) to gastric mucosal tissue. this study aimed to investigate the frequency of these genes in isolates of h. pylori from gastric biopsies and their relationship with gastritis, peptic ulcer and gastric cancer.       methods: gastric biopsy samples were obtained from patients wit...

Journal: :iranian journal of microbiology 0
hossein sedaghat department of microbiology and immunology, faculty of medicine, anatomical sciences research center, kashan university of medical sciences, kashan, iran. rezvan moniri department of microbiology and immunology, faculty of medicine, anatomical sciences research center, kashan university of medical sciences, kashan, iran ; department of microbiology and immunology, faculty of medicine, anatomical sciences research center, kashan university of medical sciences, kashan, iran. raika jamali gastroenterology department, sina hospital,tehran university of medical sciences, tehran, iran. abbas arj gastroenterology department, beheshti hospital,kashan university of medical sciences, kashan, iran. mohsen razavi zadeh gastroenterology department, beheshti hospital,kashan university of medical sciences, kashan, iran. seyed gholam abbas moosavi gastroenterology department, beheshti hospital,kashan university of medical sciences, kashan, iran.

helicobacter pylori has been strongly associated with peptic ulcer diseases, chronic gastritis, ulcers, and reported as a risk factor for gastric cancer, too. the vaculating cytotoxin (vaca), the cytotoxin associated genes (caga), the induced by contact with epithelium factor antigen (icea gene), blood adhesion binding antigen (baba2), and outer membrane protein oipa have been described as diff...

Journal: :Journal of immunology 2002
Roland Rad Markus Gerhard Roland Lang Martin Schöniger Thomas Rösch Wolfgang Schepp Ingrid Becker Hermann Wagner Christian Prinz

Presence of the Helicobacter pylori adherence factor blood group Ag-binding adhesin (BabA; binding to Lewis(b) (Le(b))) is associated with ulcer disease, adenocarcinoma, and precancerous lesions. The importance of BabA for bacterial colonization and the inflammatory response is unknown. A total of 141 antral biopsies from H. pylori-infected patients were assessed in regard to the degree of gran...

Journal: :Revista da Sociedade Brasileira de Medicina Tropical 2013
Ivy Bastos Ramis Júlia Silveira Vianna Lande Vieira da Silva Junior Andrea Von Groll Pedro Eduardo Almeida da Silva

INTRODUCTION Helicobacter pylori infection is associated with gastro-duodenal diseases. Genes related to pathogenicity have been described for H. pylori and some of them appear to be associated with more severe clinical outcomes of the infection. The present study investigates the role of cagE as a pathogenicity biomarker of H. pylori compare it to cagA, vacA, iceA and babA2 genes and correlate...

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