نتایج جستجو برای: b thalassemia
تعداد نتایج: 917848 فیلتر نتایج به سال:
The geographical distribution of Alpha and Beta-Thalassemias differ markedly. Alpha-Thalassemia being particularly prevalent in Southeast Asia and Beta-Thalassemia in the Mediterranean basin. Thalassemia syndromes are common in Saudi Arabia: the Beta-Thalassemia genes occur with variable frequency in different regions of Saudi Arabia and both B+ and Bo thalassemia have been reported. Alpha-Thal...
Background Sickle-thalassemia is an inherited hemoglobin disorder resulting from the combined heterozygosity for sicklecell and b-thalassemia genes. Myocardial iron overload in patients with sickle-thalassemia has been poorly studied; however, a report has shown no evidence of cardiac iron in a small group (n=10) of multitransfused Arab patients. The current study aims to further evaluate cardi...
Background: b-Thalassemia major is a serious medical problem.Growth retardation is commonly seen in poly-transfused b-thalassemia patients. The exact mechanism of short stature in childrenwith thalassemia major is not well understood, however, it isbelieved to be multi-factorial.Objective: To study the growth state and its relationship to growthhormone (GH) deficiency in b-thalassemia patients....
background: β-thalassemia is a common autosomal recessive disorder resulting from over 200 different mutations of beta globin genes. the aim of the present study was to identify the distribution and frequency of the most common β-thalassemia mutations among the population of isfahan province in central iran. methods: the data presented here were derived from a total of 114 β-thalassemia chro...
Combined megaloblastic anemia with thalassemia is easily masked because of the loss of macrocytosis. We performed a retrospective study to compare the major parameters in 4 groups of subjects in order to show the characteristics of patients with megaloblastic anemia and thalassemia. Group A comprised 9 patients with megaloblastic anemia and tha-lassemia, group B comprised 10 patients with uncom...
Background and Objective: Beta-thalassemia major (β-Thal) compound heterozygote of Sickle β-thalassemia (S-β Thal) are hereditary autosomal recessive disorders resulting from mutations or deletion in β-globin gene cluster. Patients with increased HbF levels having polymorphism at BCL11A site loci have shown clinical significance. The present study aimed to assess the frequency a population β-Th...
In homozygous b-thalassemia, the organ damage is mainly attributed to excessive iron deposition through the formation of oxygen free radicals. Despite appropriate transfusion and chelation therapy and low ferritin levels, patients still develop organ failure, heart failure being the main cause of death. This study was designed to determine whether the decreased antioxidant activity of the apoli...
Background and purpose: Beta-thalassemia is the most common inherited disorder in the world, especially in Iran. According to Iranian thalassemia society registry, 18616 thalassemia patients now living in Iran, which Mazandaran and Fars provinces have the most patients. Previous reports have shown that the frequency of b-thalassemia carriers is more than 10% in Mazandaran province. Although b...
MONCHANIN, G., P. CONNES, D. WOUASSI, A. FRANCINA, B. DJODA, P. E. BANGA, F. X. OWONA, P. THIRIET, R. MASSARELLI, and C. MARTIN. Hemorheology, Sickle Cell Trait, and -Thalassemia in Athletes: Effects of Exercise. Med. Sci. Sports Exerc., Vol. 37, No. 7, pp. 1086–1092, 2005. Purpose: This study investigated hemorheological parameters in response to exercise in sickle cell trait (SCT) athletes wi...
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