serum opsonic capacity against b. pertussis was studied by using quantitative chemiluminescence (cl), a method known to have several advantages over conventional methods in evaluating opsonization and phagocytosis. sera from unvaccinated infants was shown not to contain opsonins against b. pertussis and in unvaccinated infants suffering from whooping cough, no opsonins were detected. in adults ...

background adenylate cyclase toxin (cyaa) is an important virulence factor of bordetella pertussis, the causative agent of whooping cough, and a potential component of acellular pertussis vaccine. objectives in the present study the impact of invasive cyaa on oxidative activities of phagocytes was compared with the other form of this molecule to investigate the activity of different parts of mo...

Serum opsonic capacity against B. pertussis was studied by using quantitative chemiluminescence (CL), a method known to have several advantages over conventional methods in evaluating opsonization and phagocytosis. Sera from unvaccinated infants was shown not to contain opsonins against B. pertussis and in unvaccinated infants suffering from whooping cough, no opsonins were detected. In ad...

Respiratory tract infections (RTIs) are a major public health concern. This study aims to investigate the profiles and epidemiological characteristics of acute RTIs respiratory pathogens in Palestinian hospitalized patients. Clinical samples from patients with symptoms admitted between January 2011 December 2016 were referred Central Public Health Laboratory (PHCL) identify causative pathogen. ...

Bordetella pertussis and B. parapertussis are the etiological agents of pertussis, yet the former has a higher incidence and is the cause of a more severe disease, in part due to pertussis toxin. To identify other factors contributing to the different pathogenicity of the two species, we analyzed the capacity of structurally different lipooligosaccharide (LOS) from B. pertussis and LPS from B. ...

Bordetella bronchiseptica can use catecholamines to obtain iron from transferrin and lactoferrin via uptake pathways involving the BfrA, BfrD, and BfrE outer membrane receptor proteins, and although Bordetella pertussis has the bfrD and bfrE genes, the role of these genes in iron uptake has not been demonstrated. In this study, the bfrD and bfrE genes of B. pertussis were shown to be functional...

Abstract Background Pertussis is an acute respiratory tract disease caused by Bordetella pertussis. In 2014, 24.1 million pertussis cases, resulting in 160,700 deaths, were estimated to have occurred worldwide. This study aimed determine the epidemiology of among patients with clinically compatible illness who visited selected hospitals Amhara Regional State Ethiopia. Methods A cross-sectional ...

background and aims: pertussis is a highly contagious, vaccine-preventable disease. determination of the seroepidemiology of pertussis makes possible the evaluation of pertussis immunity in a population. in this study, we determined the seroprevalence of bordetella pertussis igg antibodies in different age groups in tehran, iran. materials and methods: overall, 1101 subjects between ages of 8 ...

background: the increasing incidence of pertussis among adolescents and adults in recent years is an alarming factor in transmission of the infection to non-immune infants and children. vaccination of pregnant women, immediately after delivery and before being discharged from the hospital may help to protect mothers and their newborns against the disease. decision making process, regarding mate...

Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 11, No. 4, April 2005 641 hospital with pneumonia had evidence of recent B. pertussis infection. In these persons, whether B. pertussis is a primary or secondary pathogen or an innocent bystander is not clear. Further work is needed to clarify the precise role of B. pertussis in developing adult pneumonia, the risk factors for B. pertussis–a...