INTRODUCTION Depending on the response to standard steroid therapy, nephrotic syndrome it is classified to steroid-sensitive and steroid-resistant nephrotic syndrome (SRNS). Mutations in several genes including NPHS2 have been implicated in SRNS. Gene R229Q polymorphism (p.R229Q) of NPHS2 is associated with adolescent- or adult-onset SRNS in European and South American populations. We investiga...

Introduction: Recurrent Pregnancy Loss (RPL) is a heterogeneous disease which consisting of three or more successive abortions before 20 weeks of pregnancy. The cytokines that secreted by Th1 cells (IL-1, TNFα and IFNγ) were described as etiologic factors in RPL. The aim of this study was investigate to association between recurrent pregnancy loss and IL-1 receptor antagonist gene (IL-1RN) intr...

BACKGROUND The variable numbers of tandem-repeat (VNTR) alleles at the phenylalanine hydroxylase (PAH) gene have been used in carrier detection and prenatal diagnosis in phenylketonuria families. This study was carried out to analyze VNTR alleles at the PAH gene in Iranian Azeri Turkish population. METHODS In this study, 200 alleles from general population were studied by PCR. RESULTS The f...

in this research azeri negative sentences are scrutinized with a focus on negative concord item (nci) s. linguists such asenç (1998), kornfilt (1997) and progovac (2005) assert that turkish and azeri lack negative concord item but we put forward a claim in the contrary. our purpose is to prove the existence of nci in azeri turkic. this paper includes an introduction to negative markers and spec...

OBJECTIVES To identify the frequency and distribution of familial Mediterranean fever (FMF) gene (MEFV) mutations among Azeri Turkish patients from northwestern Iran. METHODS One hundred ninety unrelated patients were referred by specialists to the Molecular-Medical Genetic Center of Tabriz. A clinical diagnosis of FMF was made according to published criteria. Mutation screening of the MEFV g...

introduction reelin gene (reln) codes a large extracellular matrix glycoprotein with serine protease activity and is implicated in the modulation of neuronal signaling, synaptic transmission and plasticity. the reelin plays a fundamental and pivotal role in the development of laminar structures and may be one of the loci contributing to the positive linkage between chromosome 7q and autistic di...

promoter polymorphism of cytokine genes may lead to inter-individual differences in cytokine levels, therefore, polymorphisms may associate with susceptibility to infectious diseases. in this study, we investigated a possible association between interleukin-10 (il-10) -1082a⁄g (rs1800896) and interferon (ifn)-gamma +874t/a (rs2430561) promoter polymorphisms and tuberculosis (tb) in the azeri po...

Introduction Reelin gene (RELN) codes a large extracellular matrix glycoprotein with serine protease activity and is implicated in the modulation of neuronal signaling, synaptic transmission and plasticity. The reelin plays a fundamental and pivotal role in the development of laminar structures and may be one of the loci contributing to the positive linkage between chromosome 7q and autistic di...