نتایج جستجو برای: azaheterocycles
تعداد نتایج: 47 فیلتر نتایج به سال:
The interaction of 2-ethoxymethylidene-3-oxo esters and their analogues with 5-aminotetrazole is an efficient synthetic approach to novel azaheterocycles. 2-Ethoxymethylidene-3-oxo esters bearing alkyl substituents react with 5-aminotetrazole to form ethyl 2-azido-4-alkylpyrimidine-5-carboxylates which are capable of subsequent nucleophilic substitution. The use of diethyl 2-ethoxymethylidenema...
The pace and the scope of new molecules design is often constrained by limitations in synthetic chemistry. azaheterocyclic amidrazones are particular interest for bioisosteric considerations drug discovery. However, lack efficient access has undoubtedly hampered their occurrence chemical space. Our current results describe a robust relying on cyclization aminohydrazine presence various orthoest...
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