AIMS To describe the theory and develop an automated virtual slide screening system. Theoretical considerations. Tissue-based diagnosis separates into (a) sampling procedure to allocate the slide area containing diagnostic information, and (b) evaluation of diagnosis from the selected area. Nyquist's theorem broadly applied in acoustics, serves to presetting the sampling accuracy. Tissue-based ...

Computer-Aided Diagnosis (CAD) systems for pathologists can act as an intelligent digital assistant supporting automated grading and morphometric-based discovery of tissue features that are important in cancer diagnosis and patient prognosis. Automated image segmentation is an essential component of computer-based grading in CAD. We describe a novel tissue segmentation algorithm using local fea...

Skincancer is a deadly malignancy. Incomplete D.N.A. repair in skin cells causeshereditary mutations and cancer. Early cancer easier to treat since itspreads slowly other body areas. As result, the optimal time find it isduring its infancy. Because of rising frequency cancer, highmortality rate, high cost medical treatment, early detection skincancer symptoms essential. Researchers have created...

background: ultrasound propagation velocity was measured experimentally in normal, fibroadenoma and ductal carcinoma breast tissues, in order to distinguish normal breast tissue from tumors. materials and methods: in quantitative measurements of ultrasound velocity, 403 breast tissue images were selected, comprising 130 normal breast tissue, 130 fibroadenoma, and 143 ductal carcinoma tumors. th...

introduction breast cancer is the second cause of mortality among women. early detection of it can enhance the chance of survival. screening systems such as mammography cannot perfectly differentiate between patients and healthy individuals. computer-aided diagnosis can help physicians make a more accurate diagnosis. materials and methods regarding the importance of separating normal and abnorm...

Background: With advances in medical imaging systems, digital dermoscopy has become one of the major imaging modalities in the analysis of skin lesions. Thus, automated segmentation or border detection has a great impact on the subsequent steps of skin cancer computer-aided diagnosis using demoscopy images. Since dermoscopy images suffer from artifacts such as shading and hair, there is a need ...

rhabdomyosarcomas are the most common soft tissue sarcoma in adult and children that accompany with skeletal muscle differentiation. skin metastasis of rhabdomyosarcomas is unusual and has only been sporadically reported in literature. in this paper we present a case of skin metastasis of rhabdomyosarcoma in an 8-year-old girl that has treated with chemotherapy.

results thirty-four patients were hyperglycemic and 127 non diabetic. sensitivity, specificity, positive predictive value and negative predictive value of fdg-pet/ct were 90%, 88%, 87% and 91% in non diabetic and 82%, 92%, 95% and 73% in hyperglycemic patients, respectively. overall, the accuracy was higher in non diabetic than hyperglycemic patients (89% vs. 85%). conclusions accuracy of fdg-p...

receptors and proteins are overexpressed in many human cancer cell membranes rather than normal tissues and are considered as the main molecular targets. specific tumor- targeting molecules which have high affinity for these receptors can be valuable tools as carrier molecules for targeted cancer therapy and imaging. pharmacokinetics and bioavailability of diagnostic and therapeutic agents are ...

In this paper we address the problem of nuclear segmentation in cancer tissue images, that is critical for specific protein activity quantification and for cancer diagnosis and therapy. We present a fully-automated morphology-based technique able to perform accurate nuclear segmentations in images with heterogeneous staining and multiple tissue layers and we compare it with an alternate semi-au...