Autoimmune pancreatitis is a new nosological entity in which a lymphocytic infiltration of the exocrine pancreas is involved. The concomitant onset of autoimmune pancreatitis and type 1 diabetes has been recently described suggesting a unique immune disturbance that compromises the pancreatic endocrine and exocrine functions. We report a case of type1 diabetes onset associated with an autoimmun...

CONTEXT Autoimmune pancreatitis is a rare but increasingly recognised condition with unique clinical, immunological and histological features. We report the first case of autoimmune pancreatitis associated with spontaneous splenic haemorrhage. CASE REPORT A 75-year-old man presented with severe epigastric pain radiating to the back associated with nausea and vomiting. A CT-scan of his abdomen...

After standard laboratory and imaging studies no causes are identified in nearly 30% of chronic pancreatitis. Japanese authors have helped us to decrease the percentage of so-called idiopathic pancreatitis because they have identified a new clinical entity of pancreatitis: the autoimmune pancreatitis [1]. In the past few years, the frequency of new diagnoses of pancreatitis due to this new enti...

Background: Autoimmune pancreatitis (AIP) can present as pancreatic mass mimicking malignancy. However, it has specific histomorphology and immunohistology which in clinical context can be diagnostic. Aim: To retrospectively analyze pancreatic resections done for pancreatic head masses to identify cases of autoimmune pancreatitis. Methods: Hematoxylin and eosin stained slides of pancreatic rese...

Type 2 autoimmune pancreatitis, an increasingly recognized etiology of pancreatitis in patients less than 20 years old, has characteristically been diagnosed with the histological finding of duct-centric pancreatitis in a patient who lacks elevated serum immunoglobulin G4. We present the case of a nonobese 15-year-old male, without any chronic medical conditions, who presented with the chief co...

Autoimmune pancreatitis is a rare but important cause of pancreatitis that is becoming increasingly recognized in the West. Lymphoplasmacytic sclerosing pancreatitis (LPSP) is a benign form of chronic pancreatitis characterized clinically by infrequent attacks of abdominal pain, jaundice, and weight loss, and pathologically by focal or diffuse chronic or lymphoplasmacytic inflammatory infiltrat...

RATIONALE Autoimmune pancreatitis is a form of chronic pancreatitis, characterized by diffused enlargement of the pancreas and irregular narrowing of the main pancreatic duct. The theory that portal hypertension is associated with autoimmune pancreatitis has not been emphasized. In addition, only a few studies report that the gastrointestinal tract hemorrhage caused by portal hypertension is as...