Objectives We developed a simple non-invasive I-123-N-isopropyl-p-iodoamphetamine (123I-IMP) quantification method by analyzing chest RI-angiography and single photon emission computed tomography (SPECT) images based on the microsphere model (SIMS method). Theoretically, the SIMS method could be changed to the simple non-invasive ARG (SIARG) method by modifying the integrated washout ratio (WR)...

BACKGROUND Before furin can act on protein substrates, it must go through an ordered process of activation. Similar to many other proteinases, furin is synthesized as a zymogen (profurin) which becomes active only after the autocatalytic removal of its auto-inhibitory prodomain. We hypothesized that to activate profurin its prodomain had to be removed and, in addition, the emerging enzyme's N-t...

Abstract Introduction. Research in the field of protein-bound phosphohistidine phosphorylation has been hampered by the difficulties in analysis and detection of phosphohistidine. Therefore a screening method was developed primarily for the analysis of phosphohistidine phosphatase 1 (PHPT1) activity. Methods. A highly positively charged substrate, Ac-Val-Arg-Leu-Lys-His-Arg-Lys-Leu-Arg-pNA, con...

background: nasal fracture is a common fracture due to trauma. gold standard method in diagnosis of nasal fracture is clinical examination and radiography is used in legal situation. recently, ultrasound is recommended as a noninvasive and simple method in diagnosis of nasal fracture. this study investigates the role of ultrasound in diagnosis of nasal fracture. methods: 126 cases with suspecte...

Auto-ophthalmoscopy, the process by which one's own fundus can be viewed, is an old technique which has been subject to many slight refinements throughout the years. Purkinje described 3 methods by which an impression of the vascular system could be obtained as far back as the 1820s (see von Helmholtz'). The reason why ordinarily we do not perceive the outline of our eyes' vascular system is be...

The purpose of this study is to examine the correlation of measured regional cerebral blood flow (rCBF) by means of a new microsphere method (non-invasive microsphere method), to the autoradiography (ARG) method, which is an established quantification method for 123I-IMP brain SPECT. The non-invasive microsphere (NIMS) method and ARG method were simultaneously applied to 30 patients, and quanti...

Background & Aims: Cervical spine is prone to various abnormalities and sport injuries. There is still no non-aggressive measurement instrument with high reliability for easy and rapid assessment of cervical spine secondary complications. The aim of this research was to investigate the validity of goniometric method for cervical lordosis measurement through radiography. Method: In this study, 1...