OBJECT Atypical meningioma often recurs even after resection. As a salvage modality, radiotherapy or stereotactic radiosurgery (SRS) is attempted for this aggressive tumor. This retrospective study was performed to evaluate the efficacy of SRS that involved Gamma Knife surgery (GKS) for atypical meningioma. METHODS The authors reviewed records from 22 patients with histologically proven atypi...

The mutations that occur in the p53 tumor suppressor gene have been studied in various human malignant tumors. However, little is known about this gene in meningiomas. To investigate the relationship and frequency of p53 gene mutations, the p53 polymerase chain reaction-single stranded conformational polymorphism (PCR-SSCP) and immunohistochemical study were performed on the 41 intracranial men...

DESCRIPTION A 65-year-old woman comes for headache management. Few years ago, she was diagnosed with a ‘single benign tumour of the anterior part of the brain’. A new contrast CT brain scan was done (figures 1 and 2); as she was claustrophobic, brain MRI was not ordered. The mass they have referred to was most likely a falcine meningioma. In addition, there is an oval hyperdense mass at the rig...

Meningioma rarely manifests as a subarachnoid hemorrhage (SAH), and invasion directly into a major intracranial artery is extremely rare. To the best of our knowledge, meningioma presenting with an SAH associated with major intracranial arterial invasion has never been reported. We present a case of sphenoid ridge meningotheliomatous meningioma manifesting as an SAH without pathologically atypi...

Background: Meningiomas are slow-growing neoplasms, accounting for 20% of all primary intracranial neoplasms and 25% intraspinal tumors. Atypical anaplastic meningiomas infrequent, representing fewer than 5% meningiomas. Unusually, they can show aggressive behavior, extracranial metastases extremely rare, approximately 0.1% reported cases. Case Description: Fifty-six-year-old male patient diagn...

Chordoid meningioma, classified as atypical meningioma according to the World Health Organisation (WHO) classification, is a rare subtype, which represents only 0.5% of all meningiomas and is associated with a high incidence of recurrence. Multiple intracranial meningiomas are rare in non-neurofibromatosis patients. We present a female patient with both of these rare types of meningioma. The pa...

Dr. Raphael Vicente Alves – Rua Estado de Israel 907 / 31 04022-002 São Paulo SP Brasil. E-mail: [email protected] Co-existing fibrous dysplasia and meningothelial meningioma is extremely rare. A search at “PubMed” (U.S. National Library of Medicine) with terms “fibrous”, “dysplasia” and “meningioma” demonstrated a total of 7 cases reported. Three cases in association with McCune-Albri...

Meningioma constitutes 27% of primary CNS tumours. It rarely metastasizes to distant sites (< 0.1%). Here, we present a case report of primary atypical intracranial meningioma metastasizing to liver and bone after 4 years of surgery and postoperative radiotherapy presenting with multiple episodes of hypoglycemia.

SUMMARY We report an unusual case of atypical cystic meningioma of the trigeminal nerve proved by histology in a 15-year-old white girl. A review of the literature showed that this is only the second reported case of a meningioma of the trigeminal nerve without dural attachment and the first occurrence in a pediatric patient.

A correlation between radiation therapy and cavernoma has been suspected since 1994. Since then, only a few cases of radio-induced cavernomas have been reported in the literature (85 patients). Most of them were children, and the most frequent original tumour had been medulloblastoma. The authors report a case of two cystic cavernous angiomas after radiation therapy for atypical meningioma in a...