We report the effects that sectioning the superior ovarian nerve of infantile female rats has on their follicular development at different ages before puberty. Compared with the control group, sham-operated animals showed a significant decrease in the number of measured follicles in right and left ovaries, although no difference in the follicular atresia ratio was observed. Animals with a secti...

Glucocorticoids modulate ovarian function in cattle. However, their regulatory mechanisms have not been fully elucidated. In the present study, we examined gene expression of two glucocorticoid-metabolizing enzymes, a bidirectional 11β-HSD type 1 (11HSD1) and a dehydrogenase 11β-HSD type 2 (11HSD2), and glucocorticoid receptor (GR) in bovine follicles during follicular maturation and atresia. G...

The immunohistochemical localization of the intermediate filaments desmin, vimentin and smooth muscle actin (SMA) in the ovary of the emu was described in the present study. The cortical region of the ovary contained developing and atretic primordial, pre-vitellogenic and vitellogenic follicles. Vimentin immunostaining was demonstrated in the granulosa cell layer of primordial, pre-vitellogenic...

In this study the effect of cadmium, cadmium+selenium and cadmium+zinc administration on the ovarian structure in Japanese quails was studied. The morphometric analysis of the relative volume of primary follicles detected the highest value in control group with a similar value in the group with administration of cadmium with selenium. Lower relative volume is reported in group with cadmium and ...

Follicular populations were investigated in female F344/N rats to better understand the aging process of the rat ovary. Ovaries dissected at various ages (spanning 1-36 months old) were submitted for histological examination. The total number of primordial, growing (primary and secondary), tertiary, and atretic follicles as well as corpora lutea (CL) were counted in hematoxylin-eosin- and azoca...

The fate of the follicular basal lamina during atresia was investigated using bovine follicles, in which different follicle phenotypes have been observed. These phenotypes include: healthy follicles with rounded basal granulosa cells with an aligned basal lamina or follicles with columnar basal granulosa cells with a basal lamina of many loops (loopy), and atretic follicles in which either the ...

Monocrotophos a organophosphate pesticide was administered orally at doses of 1.6, 3.3, 6.6, 10 and 13 mg/kg body weight/day to normal virgin Swiss albino mice for 30 days. The vaginal smear and body weight of the mice were recorded daily and mice were sacrificed on 31st day. The ovaries from each animal was serially sectioned and stained for follicular studies. Estrous cycle was affected by sh...

The present study aimed to determine if gossypol interferes with ovarian follicles in rats. Twenty-four female Wistar rats were assigned to two equal groups: one control group and the other dosed with gossypol (25 mg/kg/day, subcutaneously) for 15 days. Ovarian follicles were histologically classified according to the stage of development and as normal or atretic. Gossypol treatment reduced the...

Rabbit ovarian microvasculature, with particular regard to developing and atretic follicles, was studied by scanning electron microscopy (SEM) of vascular corrosion casts. The microvascular network of the follicles was arranged in typical round plexuses of varying shape and size. Four different morphological types of vascular plexuses supplied the follicles: Type 1 (100-250 microns in diameter)...

The present study deals with the morphological changes of the degenerating primordial and primary follicles induced by gamma-radiation. Prepubertal female mice of 3 weeks old ICR strain were gamma-irradiated with the dose of LD(80(30)) (8.3 Gy). The ovaries were collected at 3, 6 and 12 h after irradiation. The largest cross-sections were prepared by histological semithin sections for microscop...