ADA800671 unclassified secret Approved for public release; distribution is unlimited. This document is part of the Air Technical Index [ATI] collection. The ATI collection is over 50 years old and was imaged from roll film. The collection has deteriorated over time and is in poor condition. DTIC has reproduced the best available copy utilizing the most current imaging technology. ATI documents ...

This document is part of the Air Technical Index [ATI] collection. The ATI collection is over 50 years old and was imaged from roll film. The collection has deteriorated over time and is in poor condition. DTIC has reproduced the best available copy utilizing the most current imaging technology. ATI documents that are partially legible have been included in the DTIC collection due to their hist...

An anesthetic mixture of medetomidine (MED), midazolam (MID), and butorphanol (BUT) has been used in laboratory animals. We previously reported that this anesthetic mixture produced closely similar anesthetic effects in BALB/c and C57BL/6J strains. We also demonstrated the efficacy of atipamezole (ATI), an antagonist of MED that produced quick recovery from anesthesia in mice. Anesthetics have ...

The phase information in along-track interferometry (ATI) SAR images is a measure of the Doppler shift of the backscattered signal and thus of the line-of-sight velocity of the scatterers. This interferometric velocity is the sum of the orbital motion of water particles from the swell, phase velocities of the Bragg waves, and ocean surface currents. While the advent of ATI SAR provided us with ...

Infliximab is an anti-tumor necrosis factor (TNF) used for treatment of inflammatory bowel disease (IBD) as well as rheumatoid arthritis, psoriasis, and other inflammatory conditions. Antibodies to infliximab (ATI) develop in approximately 45% of infliximab-treated IBD patients and are correlated with loss of clinical response. Scarce data exist as to factors which predict infliximab immunogeni...

Therapeutic strategies aimed at achieving antiretroviral therapy (ART)-free HIV remission in infected individuals are under active investigation. Considering the vast majority of HIV-infected individuals experience plasma viral rebound upon cessation of therapy, clinical trials evaluating the efficacy of curative strategies would likely require inclusion of ART interruption. However, it is uncl...

Injured alveolar epithelial type (AT) I cells are replaced following the proliferation and transformation of ATII cells to new ATI cells. RTI(40) is an ATI cell-specific protein required for normal lung development. We hypothesized that intermediate cell types in the ATII-to-ATI cell transformation would coexpress RTI(40) and ATII cell-selective proteins. To test this hypothesis, we used a rat ...

The phase information in along-track interferometric synthetic aperture radar (along-track INSAR, ATI) images is a measure of the Doppler shift of the backscattered signal and thus of the line-of-sight velocity of the scatterers. It can be exploited for oceanic surface current measurements from aircraft or spacecraft. However, as already discussed in previous publications, the mean Doppler freq...

Alveolar epithelial type II (ATII) cells are essential for maintaining normal lung homeostasis because they produce surfactant, express innate immune proteins, and can function as progenitors for alveolar epithelial type I (ATI) cells. Although autocrine production of transforming growth factor (TGF)-β1 has been shown to promote the transdifferentiation of primary rat ATII to ATI cells in vitro...

The anesthetic mixture of medetomidine (MED), midazolam (MID) and butorphanol (BUT) produced anesthetic duration of around 40 minutes (min) in ICR mice. We reported that this anesthetic mixture produced almost the same anesthetic effects in both male and female BALB/c and C57BL/6J strains. Intraperitoneal (IP) administration of drugs has been widely used in mice. However, various injectable rou...