نتایج جستجو برای: at7519

تعداد نتایج: 29  

2014

H-MRS 375 2-deoxyglucose 85 3,30-diindolylmethane (DIM) 1269 3D culture systems 2342 450K Infinium Methylation BeadChip 781 ABCC10 696 abiraterone 2248 abiraterone acetate 1249 ABO blood type 174 access to healthcare 577 acetylation 61, 568 acinar to ductal metaplasia 817 acrylamide 987 acute promyelocytic leukaemia 874 adenocarcinoma 1993 adjuvant chemotherapy 1004, 1275 adjuvant intraperitone...

2015
Eiman Aleem Robert J. Arceci

Hematologic malignancies represent the fourth most frequently diagnosed cancer in economically developed countries. In hematologic malignancies normal hematopoiesis is interrupted by uncontrolled growth of a genetically altered stem or progenitor cell (HSPC) that maintains its ability of self-renewal. Cyclin-dependent kinases (CDKs) not only regulate the mammalian cell cycle, but also influence...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2017
Yan Kong Xinan Sheng Xiaowen Wu Junya Yan Meng Ma Jiayi Yu Lu Si Zhihong Chi Chuanliang Cui Jie Dai Yiqian Li Huan Yu Tianxiao Xu Huan Tang Bixia Tang Lili Mao Bin Lian Xuan Wang Xieqiao Yan Siming Li Jun Guo

Purpose: Effective therapies for the majority of metastatic acral melanoma patients have not been established. Thus, we investigated genetic aberrations of CDK4 pathway in acral melanoma and evaluated the efficacy of CDK4/6 inhibitors in targeted therapy of acral melanoma.Experimental Design: A total of 514 primary acral melanoma samples were examined for the copy number variations (CNV) of CDK...

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