نتایج جستجو برای: astrocytic tumors
تعداد نتایج: 181613 فیلتر نتایج به سال:
We studied the status of chromosomes 1 and 19 in 363 astrocytic and oligodendroglial tumors. Whereas the predominant pattern of copy number abnormality was a concurrent loss of the entire 1p and 19q regions (total 1p/19q loss) among oligodendroglial tumors and partial deletions of 1p and/or 19q in astrocytic tumors, a subset of apparently astrocytic tumors also had total 1p/19q loss. The presen...
The prognostic significance of 1p19q loss in astrocytic gliomas has been inconclusive.We collected 57 gliomas with total 1p19q loss from among 218 cases of WHO grade-II/III gliomas operated at Keio University Hospital between 1990 and 2010. These tumors were classified as oligodendroglial or "astrocytic" by a WHO-criteria-based institutional diagnosis. Chromosomal copy number aberrations (CNAs)...
Giant cell glioblastoma is an extremely rare variant of Glioblastoma (WHO grade IV) which is characterized by a predominance of bizarre, multinucleated giant cells. These tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. In pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. Here, we report a case of a 12-year old female pat...
Although 1p/19q codeletion is the genetic hallmark defining oligodendrogliomas, approximately 30-40% of oligodendroglial tumors have intact 1p/19q in the literature and they demonstrate a worse prognosis. This group of 1p/19q intact oligodendroglial tumors is frequently suggested to be astrocytic in nature with TP53 and ATRX mutations but actually remains under-investigated. In the present stud...
BACKGROUND AND PURPOSE Diffusion-weighted images (DWIs) have been used to study various diseases, particularly since echo-planar techniques shorten examination time. Our hypothesis was that DWIs and tumor apparent diffusion coefficients (ADCs) could provide additional useful information in the diagnosis of patients with brain tumors. METHODS Using a 1.5-T MR unit, we examined 56 patients with...
background: tumors of the central nervous system (cns) are a heterogeneous group of neoplasms with different prevalence in different sex and age groups and various parts of cns. objectives: determining the relative frequency of different types of cns tumors in different ages, sex and cns anatomical locations. materials and methods: this retrospective study was performed using pathological repor...
BACKGROUND Diffusion-weighted imaging (DWI) is a form of magnetic resonance imaging (MRI) based on measuring the random Brownian motion of water molecules within the biological tissues and is particularly useful in tumor characterization. OBJECTIVES The purpose of this study was to evaluate the diagnostic value of DW MRI and the apparent diffusion coefficient (ADC) for preoperative grading of...
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