Human spermatozoa encounter an osmotic decrease from 330 to 290 mOsm l-1 when passing through the female reproductive tract. We aimed to evaluate the role of chloride channels in volume regulation and sperm motility from patients with asthenozoospermia. Spermatozoa were purified using Percoll density gradients. Sperm volume was measured as the forward scatter signal using flow cytometry. Sperm ...

Background: The etiologic cause in near one third of male factor infertility is unknown. The percentage of men with idiopathic infertility who have been successfully treated by the empirical therapeutic modalities is not high. Objective: The aim of this study was to assay the effect of L-carnitine on sperm parameters in patients who needs intracytoplasmic sperm injection (ICSI) as a method for ...

introduction: cd59 is a complement control protein (ccp) wich exhibits its inhibitory functions by prevention of complement attack complex (max) formation. the aim of this normozoospermia, olig-astheno and azoospermia. materials and methods: the semen of 57 individual were grouped to normozoospermia (8), asthenozoospermia (21), oligo-astenozoospermia (16), and azoospermia (12) according to who ...

Introduction and Aim: Idiopathic infertility accounts for at least 30% of all cases infertility, oxidative stress has been identified as a novel developing factor in idiopathic male infertility. Oxidative occurs when antioxidant defense mechanisms are outmatched by the creation reactive oxygen species (ROS). The purpose this research was to examine impact enzymatic antioxidants (catalase supero...

Abstract Study question Is there a relationship between the microbiota composition of semen samples used for assisted reproductive technologies (ART) and quality embryos? Summary answer The obligate anaerobes prevalence in was associated with reduced embryo patients astenozoospermia, but no difference found normozoospermic samples. What is known already success ART depends on number factors, in...

background: pentoxifylline (px) is a methyxanthin derivative that influences the sperm motion characteristics. in general, px has been reportedly effective in preserving sperm motility in vitro, also when administered orally to the asthenozoospermic patients. objective: the main objective of this prospective clinical trial study was to rule out the effect of oral administration of px on sperm p...

background: no extensive studies were done that included the use of pentoxifylline or verify its effect on the outcome of icsi in cases of mild and moderate asthenozoospermia. objective: the aim of this study was to evaluate the effect of pentoxifylline used in preparation of semen samples which doesn't need motility enhancement prior to icsi. materials and methods: the study was carried on 30 ...

background: the lipids of the spermatozoa membrane are important for the fluidity and flexibility of spermatozoa. however, spermatozoa’s lipids are the main substrates for peroxidation, which may provoke severe functional disorder of sperm. objective: the aim of this study was to investigate the fatty acids composition of spermatozoa in men with asthenozoospermia, asthenoteratozoospermia and ol...