نتایج جستجو برای: ascot
تعداد نتایج: 339 فیلتر نتایج به سال:
BACKGROUND This study examined the relationships between a newly developed older person-specific non-preference-based quality of life (QoL) instrument (Older People's Quality of Life brief questionnaire (OPQoL-brief)) and two generic preference-based instruments (the EQ-5D-3L Level (EQ-5D-3 L) and the Adult Social Care Outcomes Toolkit (ASCOT) in a community-dwelling population of Australian ol...
BACKGROUND The ICEPOP CAPability measure for Older people (ICECAP-O) and Adult Social Care Outcomes Toolkit (ASCOT) are preference-based measures for assessing quality of life (QoL) from a broader perspective than do traditional health-related QoL measures such as the EuroQol five-dimensional questionnaire (EQ-5D). Measurement properties of these instruments have not yet been directly compared....
I n r e s p o n s e : Regarding the subgroup analyses in ASCOT, as displayed in Figure 5 and Table 4 of the ASCOT-LLA paper (2), there were 7 subgroups in which a statistically significant beneficial effect of atorvastatin was not observed. However, as the authors noted and as was displayed visually in Figure 5, the proportional beneficial effect on 6 subgroups (diabetes, left ventricular hyper...
abstract background: in this study we aimed to examine the discrimination and calibration of a severity characterization of trauma (ascot) in our setting to determine whether its usage is appropriate to predict outcome of our trauma patients. methods: this study was conducted in three hospitals. all patients admitted in studied hospitals were divided randomly into two equal subgroups. in each g...
OBJECTIVE To determine the cardiovascular benefits of atorvastatin stratified by blood pressure-lowering regimen, 2.2 years after closure of the lipid-lowering arm (LLA) of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT-LLA). METHODS In ASCOT-LLA, 10,305 hypertensive patients randomized to amlodipine-based or atenolol-based therapy and with a total cholesterol 6.5 mmol/l or less were fu...
BACKGROUND In economic evaluations of care services for older adults health-related quality of life (QoL) measures such as the EQ-5D are increasingly replaced by the ICECAP-O and ASCOT, which cover a broader scope of QoL than health alone. Little is known about the content validity and feasibility of these measures. The purpose of this study was to explore the content validity and feasibility o...
BACKGROUND In economic evaluations of care services for older adults health-related quality of life (QoL) measures such as the EQ-5D are increasingly replaced by the ICECAP-O and ASCOT, which cover a broader scope of QoL than health alone. Little is known about the content validity and feasibility of these measures. The purpose of this study was to explore the content validity and feasibility o...
BACKGROUND AND PURPOSE Visit-to-visit variability in blood pressure (vBP) is associated with ischemic stroke. We sought to determine whether such variability has genetic causes and whether genetic variants associated with BP variability are also associated with ischemic stroke. METHODS A Genome Wide Association Study (GWAS) for loci influencing BP variability was undertaken in 3802 individual...
Cholesterol lowering with statin therapy has been shown to reduce cardiovascular events in a variety of patient categories, ranging from patients with established cardiovascular disease to high-risk individuals with no previous history. The degree of benefit relates primarily to a patient’s absolute risk of cardiovascular events and to the absolute reduction in low-density lipoprotein (LDL)-cho...
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