نتایج جستجو برای: ascites hepatoma
تعداد نتایج: 20136 فیلتر نتایج به سال:
Comparison of Cell Coat Acid Mucopolysaccharides of Normal Liver and Various Ascites Hepatoma Cells1
avoiding cytolysis or membrane disruption. After incuba tion, the mixtures were centrifuged, and 105,000 x g supernatants were subjected to gel filtration. The macromolecular peak fractions thus obtained contained about 2% radio activity of the whole cells or 50% radioactivity of the plasma membranes. They showed several physical and chemical features characteristic of acid mucopolysaccharides....
The electron microscope study of u ascites hepatoma cells confirms their epithelial origin. Isolated cells may occur, but they are mostly gathered to form islets. Cell surfaces exhibit microvilli. Cells are interconnected by means of microvilli and of structures similar to the epithelial "terminal bars." The cells line spaces and canaliculi similar to bile canaliculi. The cytoplasm is poorly di...
We determined the effect tunicamycin (TM), an inhibitor of protein glycosylation, had on cells in vitro that were derived from solid and ascites variants of a chemically induced rat hepatoma. Using flow microfluorometry (FMF), labelling index (LI), and population-doubling time assays, we monitored the progression of cells through the cell cycle after treatment with TM. Cells in monolayer cultur...
The effect of apple polyphenol extract (APE) on the proliferation and invasion of a rat ascites hepatoma cell line of AH109A was examined in vitro. APE suppressed both the hepatoma proliferation and invasion in a dose-dependent manner up to 200 mug/ml. Serum obtained from rats orally given APE also inhibited hepatoma proliferation and invasion when added to the culture medium. Subsequently, the...
A study of the enzymes of the glycogen pathway in Novikoff ascites hepatoma shows that glycogen synthetase has the lowest activity and that the tumour contains no high-K(m) soluble glucokinase. However, incubation of tumour cells with metabolizable sugars in vitro, or intraperitoneal administration of glucose into the tumour-bearing rat, results in glycogen accumulation by the tumour cells. Gly...
Inhibition of fermentation or of glucose uptake in the presence ofoxygen has been observed in many forms of life and is generally referred to as the 'Pasteur effect'. In most tissues, oxidative inhibition of fermentation (ethanol or lactate production) is reflected by a parallel decrease in glucose consumption. Since certain tissues utilize lactate significantly, estimation of the Pasteur effec...
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